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ATF7IP elisa kit :: Canine Activating transcription factor 7-interacting protein 1 (ATF7IP) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7252589 ATF7IP elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Activating transcription factor 7-interacting protein 1 (ATF7IP), ELISA Kit

 Also Known As   

Canine Activating transcription factor 7-interacting protein 1 (ATF7IP) ELISA Kit

 Product Gene Name   

ATF7IP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    613644
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ATF7IP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ATF7IP purchase    MBS7252589 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Activating transcription factor 7-interacting protein 1 (ATF7IP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATF7IP. The ELISA analytical biochemical technique of the MBS7252589 kit is based on ATF7IP antibody-ATF7IP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATF7IP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATF7IP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ATF7IP elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for ATF7IP. It may not necessarily be applicable to this product.
 NCBI GI #    557440804
 NCBI GeneID    55729
 NCBI Accession #    NP_851997.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_181352.1 [Other Products]
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 UniProt Secondary Accession #    Q4G0T9; Q6P3T3; Q86XW5; Q9NVJ9; Q9NWC2; Q9Y4X8; F5GX74; G3V1U0 [Other Products]
 UniProt Related Accession #    Q6VMQ6 [Other Products]
 Molecular Weight    136,323 Da
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 NCBI Official Full Name    activating transcription factor 7-interacting protein 1 isoform 1
 NCBI Official Synonym Full Names    activating transcription factor 7 interacting protein
 NCBI Official Symbol    ATF7IP [Similar Products]
 NCBI Official Synonym Symbols   
AM; MCAF; p621; MCAF1; ATF-IP
[Similar Products]
 NCBI Protein Information    activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF7-interacting protein; ATFa-associated modulator; MBD1-containing chromatin-associated factor 1
 UniProt Protein Name    Activating transcription factor 7-interacting protein 1
 UniProt Synonym Protein Names   
ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621
 Protein Family    Activating transcription factor 7-interacting protein
 UniProt Gene Name    ATF7IP [Similar Products]
 UniProt Synonym Gene Names    MCAF; MCAF1; ATF-IP; hAM [Similar Products]
 UniProt Entry Name    MCAF1_HUMAN
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 NCBI Summary for ATF7IP    ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]
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 UniProt Comments for ATF7IP    ATF7IP: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3). Facilitates telomerase TERT and TERC gene expression by SP1 in cancer cells. Belongs to the MCAF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 12p13.1

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus

Molecular Function: protein binding; ATPase activity; transcription corepressor activity

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; viral reproduction; positive regulation of transcription, DNA-dependent; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of transcriptional preinitiation complex assembly
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 Research Articles on ATF7IP    1. We demonstrated the importance of Aire's interaction with the ATF7ip-MBD1 protein complex in maintaining central tolerance
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ATF7IP elisa kitDiseases associated with ATF7IP elisa kit
 Reference Product  PubMed Publications
 MBD1 elisa kit  >9 publications with ATF7IP and MBD1
 SETDB1 elisa kit  >5 publications with ATF7IP and SETDB1
 SP1 elisa kit  >4 publications with ATF7IP and SP1
 SUMO3 elisa kit  >2 publications with ATF7IP and SUMO3
 ERCC3 elisa kit  >1 publications with ATF7IP and ERCC3
 SUMO2 elisa kit  >1 publications with ATF7IP and SUMO2
 Disease Name  Pubmed Publications
 Testicular Neoplasms Antibodies  >7 publications with ATF7IP and Testicular Neoplasms
 Neoplasms, Germ Cell and Embryonal Antibodies  >7 publications with ATF7IP and Neoplasms, Germ Cell and Embryonal
 Ovarian Diseases Antibodies  >2 publications with ATF7IP and Ovarian Diseases
 Ovarian Neoplasms Antibodies  >2 publications with ATF7IP and Ovarian Neoplasms
 Precancerous Conditions Antibodies  >1 publications with ATF7IP and Precancerous Conditions
 Prostatic Neoplasms Antibodies  >1 publications with ATF7IP and Prostatic Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with ATF7IP and Neoplasm Metastasis
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with ATF7IP and Prenatal Exposure Delayed Effects
 Prenatal Injuries Antibodies  >1 publications with ATF7IP and Prenatal Injuries
 Prostatic Diseases Antibodies  >1 publications with ATF7IP and Prostatic Diseases
Organs/Tissues associated with ATF7IP elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with ATF7IP and Blood
 Testis Antibodies  >1 publications with ATF7IP and Testis
 Embryonic Tissue Antibodies  >1 publications with ATF7IP and Embryonic Tissue
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