NP_056324.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
11,444 Da
NCBI Official Full Name
adaptin ear-binding coat-associated protein 1
NCBI Official Synonym Full Names
NECAP endocytosis associated 1
NCBI Official Synonym Symbols
NCBI Protein Information
adaptin ear-binding coat-associated protein 1
UniProt Protein Name
Adaptin ear-binding coat-associated protein 1
UniProt Synonym Protein Names
NECAP endocytosis-associated protein 1; NECAP-1
UniProt Synonym Gene Names
UniProt Entry Name
NECP1_HUMAN
NCBI Summary for NECAP1
This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
UniProt Comments for NECAP1
NECAP1: Involved in endocytosis. Belongs to the NECAP family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 12p13.31
Cellular Component: clathrin vesicle coat; plasma membrane; coated pit
Biological Process: protein transport; endocytosis
Disease: Epileptic Encephalopathy, Early Infantile, 21
Research Articles on NECAP1
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Pathways associated with NECAP1 elisa kit
Organs/Tissues associated with NECAP1 elisa kit
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