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AIFM2 elisa kit :: Canine Apoptosis-inducing factor 2 (AIFM2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7240010 AIFM2 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Apoptosis-inducing factor 2 (AIFM2), ELISA Kit

 Also Known As   

Canine Apoptosis-inducing factor 2 (AIFM2) ELISA Kit

 Product Gene Name   

AIFM2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    605159
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AIFM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AIFM2 purchase    MBS7240010 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apoptosis-inducing factor 2 (AIFM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AIFM2. The ELISA analytical biochemical technique of the MBS7240010 kit is based on AIFM2 antibody-AIFM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AIFM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AIFM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for AIFM2 elisa kit    Cell Biology
NCBI/Uniprot data below describe general gene information for AIFM2. It may not necessarily be applicable to this product.
 NCBI GI #    311082415
 NCBI GeneID    84883
 NCBI Accession #    NP_001185625.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001198696.1 [Other Products]
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 UniProt Secondary Accession #    Q63Z39; B3KXI0 [Other Products]
 UniProt Related Accession #    Q9BRQ8 [Other Products]
 Molecular Weight    36,520 Da
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 NCBI Official Full Name    apoptosis-inducing factor 2
 NCBI Official Synonym Full Names    apoptosis-inducing factor, mitochondrion-associated, 2
 NCBI Official Symbol    AIFM2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    apoptosis-inducing factor 2; p53-responsive gene 3 protein; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death
 UniProt Protein Name    Apoptosis-inducing factor 2
 UniProt Synonym Protein Names   
Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein
 Protein Family    Apoptosis-inducing factor
 UniProt Gene Name    AIFM2 [Similar Products]
 UniProt Synonym Gene Names    AMID; PRG3 [Similar Products]
 UniProt Entry Name    AIFM2_HUMAN
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 NCBI Summary for AIFM2    This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010]
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 UniProt Comments for AIFM2    AIFM2: Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. Belongs to the FAD-dependent oxidoreductase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral; EC 1.-.-.-; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: extracellular space; mitochondrial outer membrane; mitochondrion; cytoplasm; integral to membrane; lipid particle; cytosol

Molecular Function: NADH dehydrogenase (ubiquinone) activity; DNA binding; FAD binding; electron-transferring-flavoprotein dehydrogenase activity

Biological Process: apoptotic mitochondrial changes; positive regulation of apoptosis
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 Research Articles on AIFM2    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AIFM2 elisa kitPathways associated with AIFM2 elisa kit
 Reference Product  PubMed Publications
 TP53 elisa kit  >1 publications with AIFM2 and TP53
 Products by Pathway  Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
Diseases associated with AIFM2 elisa kitOrgans/Tissues associated with AIFM2 elisa kit
 Disease Name  Pubmed Publications
 Adenoma Antibodies  >1 publications with AIFM2 and Adenoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with AIFM2 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >1 publications with AIFM2 and Breast Neoplasms
 Kidney Diseases Antibodies  >1 publications with AIFM2 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >1 publications with AIFM2 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >1 publications with AIFM2 and Embryonic Tissue
 Brain Antibodies  >1 publications with AIFM2 and Brain
 Prostate Antibodies  >1 publications with AIFM2 and Prostate
 Kidney Antibodies  >1 publications with AIFM2 and Kidney
 Lung Antibodies  >1 publications with AIFM2 and Lung
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