NP_066190.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,431 Da
NCBI Official Full Name
aquaporin-9
NCBI Official Synonym Full Names
aquaporin 9
NCBI Protein Information
aquaporin-9; aquaglyceroporin-9; small solute channel 1
UniProt Protein Name
Aquaporin-9
UniProt Synonym Protein Names
Aquaglyceroporin-9; Small solute channel 1
UniProt Synonym Gene Names
UniProt Entry Name
AQP9_HUMAN
NCBI Summary for AQP-9
The aquaporins are a family of water-selective membrane channels. The protein encoded by this gene allows passage of a wide variety of noncharged solutes. It stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. [provided by RefSeq, Jul 2008]
UniProt Comments for AQP-9
AQP9: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Membrane protein, integral; Transporter; Transporter, aquaporin family; Membrane protein, multi-pass; Channel, misc.
Chromosomal Location of Human Ortholog: 15q
Cellular Component: intracellular membrane-bound organelle; integral to plasma membrane; basolateral plasma membrane; integral to membrane; plasma membrane
Molecular Function: purine transmembrane transporter activity; water transporter activity; amine transmembrane transporter activity; pyrimidine transmembrane transporter activity; urea transmembrane transporter activity; polyol transmembrane transporter activity; carboxylic acid transmembrane transporter activity; water channel activity; porin activity; glycerol channel activity
Biological Process: polyol transport; glycerol transport; cellular water homeostasis; metabolic process; amine transport; water transport; carboxylic acid transport; excretion; response to osmotic stress; purine transport; response to organic substance; water homeostasis; response to mercury ion; transport; pyrimidine transport; canalicular bile acid transport; immune response; transmembrane transport
Research Articles on AQP-9
Precautions
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Products associated with AQP-9 elisa kit
Pathways associated with AQP-9 elisa kit
Diseases associated with AQP-9 elisa kit
Organs/Tissues associated with AQP-9 elisa kit
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