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BRD4 elisa kit :: Canine Bromodomain-containing protein 4 (BRD4) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7207126 BRD4 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Bromodomain-containing protein 4 (BRD4), ELISA Kit

 Also Known As   

Canine Bromodomain-containing protein 4 (BRD4) ELISA Kit

 Product Gene Name   

BRD4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    608749
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of BRD4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for BRD4 purchase    MBS7207126 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bromodomain-containing protein 4 (BRD4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BRD4. The ELISA analytical biochemical technique of the MBS7207126 kit is based on BRD4 antibody-BRD4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BRD4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BRD4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for BRD4 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for BRD4. It may not necessarily be applicable to this product.
 NCBI GI #    19718731
 NCBI GeneID    23476
 NCBI Accession #    NP_490597.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_058243.2 [Other Products]
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 UniProt Secondary Accession #    O60433; Q4G0X8; Q86YS8; Q96PD3 [Other Products]
 UniProt Related Accession #    O60885 [Other Products]
 Molecular Weight    88,289 Da
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 NCBI Official Full Name    bromodomain-containing protein 4 isoform long
 NCBI Official Synonym Full Names    bromodomain containing 4
 NCBI Official Symbol    BRD4 [Similar Products]
 NCBI Official Synonym Symbols   
CAP; MCAP; HUNK1; HUNKI
[Similar Products]
 NCBI Protein Information    bromodomain-containing protein 4; bromodomain-containing 4; chromosome-associated protein
 UniProt Protein Name    Bromodomain-containing protein 4
 UniProt Synonym Protein Names   
Protein HUNK1
 Protein Family    Bromodomain-containing protein
 UniProt Gene Name    BRD4 [Similar Products]
 UniProt Synonym Gene Names    HUNK1 [Similar Products]
 UniProt Entry Name    BRD4_HUMAN
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 NCBI Summary for BRD4    The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for BRD4    BRD4: an atypical protein kinase of the Brd family. Contains a double bromodomain. Binds to chromatin and regulates cell cycle progression at multiple stages. Associates with chromosomes during mitosis. The cognate gene is the chromosome 19 target of translocation t(15;19)(q13;p13.1), resulting in the BRD4-NUT oncogene identified in a lethal carcinoma of young people. Binds to papillomavirus E2 protein and is required for its transforming ability. Two alternatively spliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, atypical; Protein kinase, Ser/Thr (non-receptor); ATYPICAL group; BRD family

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: nucleoplasm; transcription elongation factor complex b; condensed nuclear chromosome; nuclear chromatin; cytoplasm; chromosome; nucleus

Molecular Function: protein binding; DNA binding; p53 binding; chromatin binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; transcription, DNA-dependent; viral reproduction; protein amino acid phosphorylation; inner cell mass cell proliferation; chromosome segregation; G1/S-specific transcription in mitotic cell cycle; chromatin remodeling; positive regulation of RNA elongation from RNA polymerase II promoter; regulation of inflammatory response; positive regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus; positive regulation of DNA binding
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 Research Articles on BRD4    1. BRD4 associates with p53 in DNMT3A-mutated leukemia cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BRD4 elisa kitDiseases associated with BRD4 elisa kit
 Reference Product  PubMed Publications
 CDK9 elisa kit  >27 publications with BRD4 and CDK9
 HEXIM1 elisa kit  >13 publications with BRD4 and HEXIM1
 CCNT1 elisa kit  >6 publications with BRD4 and CCNT1
 RFC1 elisa kit  >1 publications with BRD4 and RFC1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >22 publications with BRD4 and Inflammation
 Breast Neoplasms Antibodies  >10 publications with BRD4 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >9 publications with BRD4 and Neoplasm Metastasis
 Musculoskeletal Diseases Antibodies  >8 publications with BRD4 and Musculoskeletal Diseases
 Nervous System Diseases Antibodies  >6 publications with BRD4 and Nervous System Diseases
 Fibrosis Antibodies  >3 publications with BRD4 and Fibrosis
 Hypertrophy Antibodies  >3 publications with BRD4 and Hypertrophy
 Necrosis Antibodies  >3 publications with BRD4 and Necrosis
 Adenocarcinoma Antibodies  >3 publications with BRD4 and Adenocarcinoma
 Heart Diseases Antibodies  >2 publications with BRD4 and Heart Diseases
Organs/Tissues associated with BRD4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >28 publications with BRD4 and Testis
 Blood Antibodies  >19 publications with BRD4 and Blood
 Lung Antibodies  >15 publications with BRD4 and Lung
 Bone Antibodies  >9 publications with BRD4 and Bone
 Prostate Antibodies  >7 publications with BRD4 and Prostate
 Brain Antibodies  >7 publications with BRD4 and Brain
 Lymph Node Antibodies  >5 publications with BRD4 and Lymph Node
 Bone Marrow Antibodies  >5 publications with BRD4 and Bone Marrow
 Lymph Antibodies  >5 publications with BRD4 and Lymph
 Thymus Antibodies  >4 publications with BRD4 and Thymus
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