NP_001796.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,603 Da
NCBI Official Full Name
CCAAT/enhancer-binding protein epsilon
NCBI Official Synonym Full Names
CCAAT/enhancer binding protein epsilon
NCBI Protein Information
CCAAT/enhancer-binding protein epsilon
UniProt Protein Name
CCAAT/enhancer-binding protein epsilon
UniProt Synonym Gene Names
NCBI Summary for CEBPE
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for CEBPE
C/EBP-epsilon: C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Belongs to the bZIP family. C/EBP subfamily.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 14q11.2
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: cytokine biosynthetic process; defense response; defense response to bacterium; granulocyte differentiation; macrophage differentiation; phagocytosis; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Disease: Specific Granule Deficiency
Research Articles on CEBPE
Precautions
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Disclaimer
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Products associated with CEBPE elisa kit
Pathways associated with CEBPE elisa kit
Diseases associated with CEBPE elisa kit
Disease Name |
Pubmed Publications |
Neoplasms Antibodies |
>24 publications with CEBPE and Neoplasms |
Leukemia, Myeloid Antibodies |
>22 publications with CEBPE and Leukemia, Myeloid |
Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies |
>12 publications with CEBPE and Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Leukemia, Promyelocytic, Acute Antibodies |
>10 publications with CEBPE and Leukemia, Promyelocytic, Acute |
Specific Granule Deficiency Antibodies |
>7 publications with CEBPE and Specific Granule Deficiency |
Inflammation Antibodies |
>3 publications with CEBPE and Inflammation |
Disease Models, Animal Antibodies |
>2 publications with CEBPE and Disease Models, Animal |
Epstein-Barr Virus Infections Antibodies |
>1 publications with CEBPE and Epstein-Barr Virus Infections |
Abnormalities, Multiple Antibodies |
>1 publications with CEBPE and Abnormalities, Multiple |
Blood Coagulation Disorders Antibodies |
>1 publications with CEBPE and Blood Coagulation Disorders |
Organs/Tissues associated with CEBPE elisa kit
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