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CALCRL elisa kit :: Canine Calcitonin gene-related peptide type 1 receptor (CALCRL) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7230766 CALCRL elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calcitonin gene-related peptide type 1 receptor (CALCRL), ELISA Kit

 Also Known As   

Canine Calcitonin gene-related peptide type 1 receptor (CALCRL) ELISA Kit

 Product Gene Name   

CALCRL elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    114190
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CALCRL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CALCRL purchase    MBS7230766 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Calcitonin gene-related peptide type 1 receptor (CALCRL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CALCRL. The ELISA analytical biochemical technique of the MBS7230766 kit is based on CALCRL antibody-CALCRL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CALCRL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CALCRL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CALCRL elisa kit    Neurobiology
NCBI/Uniprot data below describe general gene information for CALCRL. It may not necessarily be applicable to this product.
 NCBI GI #    5031621
 NCBI GeneID    10203
 NCBI Accession #    NP_005786.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005795.5 [Other Products]
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 UniProt Secondary Accession #    Q53S02; Q53TS5; A8K6G5; A8KAD3 [Other Products]
 UniProt Related Accession #    Q16602 [Other Products]
 Molecular Weight    52,929 Da
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 NCBI Official Full Name    calcitonin gene-related peptide type 1 receptor
 NCBI Official Synonym Full Names    calcitonin receptor-like
 NCBI Official Symbol    CALCRL [Similar Products]
 NCBI Official Synonym Symbols   
CRLR; CGRPR
[Similar Products]
 NCBI Protein Information    calcitonin gene-related peptide type 1 receptor; CGRP type 1 receptor; calcitonin receptor-like receptor
 UniProt Protein Name    Calcitonin gene-related peptide type 1 receptor
 UniProt Synonym Protein Names   
Calcitonin receptor-like receptor
 Protein Family    Calcitonin gene-related peptide type 1 receptor
 UniProt Gene Name    CALCRL [Similar Products]
 UniProt Synonym Gene Names    CGRPR; CGRP type 1 receptor [Similar Products]
 UniProt Entry Name    CALRL_HUMAN
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 UniProt Comments for CALCRL    CALCRL: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Cell cycle regulation; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q32.1

Cellular Component: integral to plasma membrane; lysosome; endoplasmic reticulum; plasma membrane; endosome

Molecular Function: G-protein coupled receptor activity; protein binding; calcitonin gene-related polypeptide receptor activity; adrenomedullin receptor activity; protein transporter activity; calcitonin receptor activity

Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; protein transport; regulation of muscle contraction; receptor internalization; positive regulation of smooth muscle cell proliferation; calcium ion transport; heart development; negative regulation of inflammatory response; positive regulation of cAMP biosynthetic process; cAMP biosynthetic process; angiogenesis; G-protein signaling, adenylate cyclase activating pathway
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 Research Articles on CALCRL    1. CRLR expression is upregulated in the fetal lung with increasing gestational age.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CALCRL elisa kitPathways associated with CALCRL elisa kit
 Reference Product  PubMed Publications
 RAMP2 elisa kit  >106 publications with CALCRL and RAMP2
 RAMP1 elisa kit  >96 publications with CALCRL and RAMP1
 RAMP3 elisa kit  >63 publications with CALCRL and RAMP3
 ADM elisa kit  >43 publications with CALCRL and ADM
 ADM2 elisa kit  >6 publications with CALCRL and ADM2
 CRCP elisa kit  >6 publications with CALCRL and CRCP
 CALCA elisa kit  >1 publications with CALCRL and CALCA
 Products by Pathway  Pathway Diagram
 Calcitonin-like Ligand Receptors Pathway antibodies  Calcitonin-like Ligand Receptors Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Endothelin Pathway antibodies  Endothelin Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with CALCRL elisa kitOrgans/Tissues associated with CALCRL elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >29 publications with CALCRL and Cardiovascular Diseases
 Hypertension Antibodies  >15 publications with CALCRL and Hypertension
 Heart Diseases Antibodies  >14 publications with CALCRL and Heart Diseases
 Inflammation Antibodies  >10 publications with CALCRL and Inflammation
 Hypertrophy Antibodies  >7 publications with CALCRL and Hypertrophy
 Kidney Diseases Antibodies  >6 publications with CALCRL and Kidney Diseases
 Edema Antibodies  >6 publications with CALCRL and Edema
 Necrosis Antibodies  >5 publications with CALCRL and Necrosis
 Fibrosis Antibodies  >4 publications with CALCRL and Fibrosis
 Fetal Death Antibodies  >3 publications with CALCRL and Fetal Death
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >67 publications with CALCRL and Vascular
 Muscle Antibodies  >51 publications with CALCRL and Muscle
 Heart Antibodies  >41 publications with CALCRL and Heart
 Kidney Antibodies  >24 publications with CALCRL and Kidney
 Brain Antibodies  >23 publications with CALCRL and Brain
 Embryonic Tissue Antibodies  >14 publications with CALCRL and Embryonic Tissue
 Lung Antibodies  >14 publications with CALCRL and Lung
 Uterus Antibodies  >12 publications with CALCRL and Uterus
 Placenta Antibodies  >10 publications with CALCRL and Placenta
 Nerve Antibodies  >9 publications with CALCRL and Nerve
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