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CSNK1E elisa kit :: Canine Casein kinase I isoform epsilon (CSNK1E) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7208239 CSNK1E elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Casein kinase I isoform epsilon (CSNK1E), ELISA Kit

 Also Known As   

Canine Casein kinase I isoform epsilon (CSNK1E) ELISA Kit

 Product Gene Name   

CSNK1E elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600863
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CSNK1E elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CSNK1E purchase    MBS7208239 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Casein kinase I isoform epsilon (CSNK1E) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CSNK1E. The ELISA analytical biochemical technique of the MBS7208239 kit is based on CSNK1E antibody-CSNK1E antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CSNK1E antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CSNK1E. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CSNK1E elisa kit    Neurobiology
NCBI/Uniprot data below describe general gene information for CSNK1E. It may not necessarily be applicable to this product.
 NCBI GI #    23199991
 NCBI GeneID    1454
 NCBI Accession #    NP_689407.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_152221.2 [Other Products]
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 UniProt Related Accession #    P49674 [Other Products]
 Molecular Weight    47,315 Da
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 NCBI Official Full Name    casein kinase I isoform epsilon
 NCBI Official Synonym Full Names    casein kinase 1, epsilon
 NCBI Official Symbol    CSNK1E [Similar Products]
 NCBI Official Synonym Symbols   
HCKIE; CKIepsilon
[Similar Products]
 NCBI Protein Information    casein kinase I isoform epsilon; CKIe; CKI-epsilon
 UniProt Protein Name    Casein kinase I isoform epsilon
 Protein Family    Casein kinase
 UniProt Gene Name    CSNK1E [Similar Products]
 UniProt Synonym Gene Names    CKI-epsilon; CKIe [Similar Products]
 UniProt Entry Name    KC1E_HUMAN
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 NCBI Summary for CSNK1E    The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]
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 UniProt Comments for CSNK1E    CK1E: an ubiquitous protein kinase of the CK1 family. Together with Dvl-1 and Frat-1 activate the Wnt signaling pathway. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. May play a role in cell cycle progression. Two splice variant isoforms have been described. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK, or NPAS2, BMAL1 or BMAL2, CK1-D and/or CK1-E, TIMELESS and the PER proteins. Interacts directly with PER1 and PER2 which may lead to their degradation. Interacts with SOCS3. Mutations in hamster and Drosophila orthologs have circadian rhythm phenotypes, and the circadian gene period (per) is a substrate in both human and fly. A coding SNP variant in human, which increases CK1 activity, is negatively associated with circadian disorder. LOF mutations and LOH seen in mammary ductal carcinoma.

Protein type: Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm; nucleus; cytosol; ribonucleoprotein complex

Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase activity

Biological Process: circadian rhythm; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; organelle organization and biogenesis; endocytosis; regulation of circadian rhythm; DNA repair; signal transduction; protein amino acid phosphorylation; regulation of cell shape; peptidyl-serine phosphorylation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; circadian regulation of gene expression; mitotic cell cycle; G2/M transition of mitotic cell cycle
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 Research Articles on CSNK1E    1. MST1 still inhibited the Wnt3A-induced phosphorylation of DVL2 (dishevelled 2) and Wnt/beta-catenin signalling by disturbing the interaction of DVL2 and CK1epsilon
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CSNK1E elisa kitPathways associated with CSNK1E elisa kit
 Reference Product  PubMed Publications
 PER3 elisa kit  >11 publications with CSNK1E and PER3
 PER1 elisa kit  >11 publications with CSNK1E and PER1
 PER2 elisa kit  >9 publications with CSNK1E and PER2
 CRY1 elisa kit  >7 publications with CSNK1E and CRY1
 CTNNB1 elisa kit  >5 publications with CSNK1E and CTNNB1
 ARNTL elisa kit  >5 publications with CSNK1E and ARNTL
 AXIN1 elisa kit  >2 publications with CSNK1E and AXIN1
 APC elisa kit  >1 publications with CSNK1E and APC
 Products by Pathway  Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Circadian Rhythm Pathway antibodies  Circadian Rhythm Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
Diseases associated with CSNK1E elisa kitOrgans/Tissues associated with CSNK1E elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >8 publications with CSNK1E and Mental Disorders
 Nervous System Diseases Antibodies  >3 publications with CSNK1E and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >1 publications with CSNK1E and Neoplasm Metastasis
 Insulin Resistance Antibodies  >1 publications with CSNK1E and Insulin Resistance
 Liver Neoplasms Antibodies  >1 publications with CSNK1E and Liver Neoplasms
 Brain Diseases Antibodies  >1 publications with CSNK1E and Brain Diseases
 Fatty Liver Antibodies  >1 publications with CSNK1E and Fatty Liver
 Kidney Diseases Antibodies  >1 publications with CSNK1E and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with CSNK1E and Blood
 Brain Antibodies  >6 publications with CSNK1E and Brain
 Liver Antibodies  >5 publications with CSNK1E and Liver
 Prostate Antibodies  >3 publications with CSNK1E and Prostate
 Nerve Antibodies  >2 publications with CSNK1E and Nerve
 Bone Antibodies  >2 publications with CSNK1E and Bone
 Pharynx Antibodies  >1 publications with CSNK1E and Pharynx
 Ovary Antibodies  >1 publications with CSNK1E and Ovary
 Kidney Antibodies  >1 publications with CSNK1E and Kidney
 Eye Antibodies  >1 publications with CSNK1E and Eye
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