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CITED4 elisa kit :: Canine Cbp/p300-interacting transactivator 4 (CITED4) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7247001 CITED4 elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cbp/p300-interacting transactivator 4 (CITED4), ELISA Kit

 Also Known As   

Canine Cbp/p300-interacting transactivator 4 (CITED4) ELISA Kit

 Product Gene Name   

CITED4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606815
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    2.5-50ng/mL
 Sensitivity    0.1ng/mL
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CITED4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CITED4 purchase    MBS7247001 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cbp/p300-interacting transactivator 4 (CITED4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 2.5-50ng/mL in biological research samples containing CITED4, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS7247001 kit is based on CITED4 antibody-CITED4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CITED4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CITED4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CITED4 elisa kit    Epigenetics and Nuclear Signaling
NCBI/Uniprot data below describe general gene information for CITED4. It may not necessarily be applicable to this product.
 NCBI GI #    19263349
 NCBI GeneID    163732
 NCBI Accession #    NP_597724.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_133467.2 [Other Products]
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 UniProt Related Accession #    Q96RK1 [Other Products]
 Molecular Weight    18,569 Da [Similar Products]
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 NCBI Official Full Name    cbp/p300-interacting transactivator 4
 NCBI Official Synonym Full Names    Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
 NCBI Official Symbol    CITED4 [Similar Products]
 NCBI Protein Information    cbp/p300-interacting transactivator 4; MRG-2; MSG1-related protein 2; transcriptional co-activator 4
 UniProt Protein Name    Cbp/p300-interacting transactivator 4
 UniProt Synonym Protein Names   
MSG1-related protein 2; MRG-2
 Protein Family    Cbp/p300-interacting transactivator
 UniProt Gene Name    CITED4 [Similar Products]
 UniProt Synonym Gene Names    MRG2; MRG-2 [Similar Products]
 UniProt Entry Name    CITE4_HUMAN
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 NCBI Summary for CITED4    The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011]
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 UniProt Comments for CITED4    CITED4: Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells. Belongs to the CITED family.

Chromosomal Location of Human Ortholog: 1p34.2|1p35-p34

Cellular Component: cytoplasm; nucleus

Molecular Function: transcription coactivator activity

Biological Process: transcription, DNA-dependent; response to estrogen stimulus; positive regulation of transcription, DNA-dependent
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 Research Articles on CITED4    1. Demethylation and histone modification can potentially reactivate CITED4 gene expression in some breast cancers and lead to changes in tumour behaviour.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CITED4 elisa kitDiseases associated with CITED4 elisa kit
 Reference Product  PubMed Publications
 TFAP2A elisa kit  >3 publications with CITED4 and TFAP2A
 TFAP2C elisa kit  >2 publications with CITED4 and TFAP2C
 TFAP2B elisa kit  >2 publications with CITED4 and TFAP2B
 EP300 elisa kit  >1 publications with CITED4 and EP300
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with CITED4 and Breast Neoplasms
 Carcinoma Antibodies  >2 publications with CITED4 and Carcinoma
 Nervous System Diseases Antibodies  >2 publications with CITED4 and Nervous System Diseases
 Hypertrophy Antibodies  >2 publications with CITED4 and Hypertrophy
 Lung Neoplasms Antibodies  >1 publications with CITED4 and Lung Neoplasms
 Fibrosis Antibodies  >1 publications with CITED4 and Fibrosis
 Adenocarcinoma Antibodies  >1 publications with CITED4 and Adenocarcinoma
 Necrosis Antibodies  >1 publications with CITED4 and Necrosis
 Inflammation Antibodies  >1 publications with CITED4 and Inflammation
Organs/Tissues associated with CITED4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with CITED4 and Muscle
 Embryonic Tissue Antibodies  >2 publications with CITED4 and Embryonic Tissue
 Brain Antibodies  >2 publications with CITED4 and Brain
 Blood Antibodies  >2 publications with CITED4 and Blood
 Kidney Antibodies  >1 publications with CITED4 and Kidney
 Liver Antibodies  >1 publications with CITED4 and Liver
 Lung Antibodies  >1 publications with CITED4 and Lung
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