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CLCN6 elisa kit :: Canine Chloride transport protein 6 (CLCN6) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7252259 CLCN6 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Chloride transport protein 6 (CLCN6), ELISA Kit

 Also Known As   

Canine Chloride transport protein 6 (CLCN6) ELISA Kit

 Product Gene Name   

CLCN6 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    602726
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CLCN6 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CLCN6 purchase    MBS7252259 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chloride transport protein 6 (CLCN6) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CLCN6. The ELISA analytical biochemical technique of the MBS7252259 kit is based on CLCN6 antibody-CLCN6 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLCN6 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLCN6. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CLCN6 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for CLCN6. It may not necessarily be applicable to this product.
 NCBI GI #    4502873
 NCBI GeneID    1185
 NCBI Accession #    NP_001277.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001286.3 [Other Products]
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 UniProt Secondary Accession #    O60818; O60819; O60820; O60821; P78520; P78521; Q17R81; Q5SNW2; A8K1T4; B4DGT7; F8W9R3 [Other Products]
 UniProt Related Accession #    P51797 [Other Products]
 Molecular Weight    94,660 Da
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 NCBI Official Full Name    chloride transport protein 6 isoform 1
 NCBI Official Synonym Full Names    chloride channel, voltage-sensitive 6
 NCBI Official Symbol    CLCN6 [Similar Products]
 NCBI Official Synonym Symbols   
CLC-6
[Similar Products]
 NCBI Protein Information    chloride transport protein 6
 UniProt Protein Name    Chloride transport protein 6
 UniProt Synonym Protein Names   
Chloride channel protein 6; ClC-6
 Protein Family    Chloride transport protein
 UniProt Gene Name    CLCN6 [Similar Products]
 UniProt Synonym Gene Names    KIAA0046; ClC-6 [Similar Products]
 UniProt Entry Name    CLCN6_HUMAN
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 NCBI Summary for CLCN6    This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012]
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 UniProt Comments for CLCN6    CLCN6: Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter. Belongs to the chloride channel (TC 2.A.49) family. ClC-6/CLCN6 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, chloride; Transporter, ion channel; Transporter

Chromosomal Location of Human Ortholog: 1p36

Cellular Component: lysosomal membrane; integral to membrane; endosome membrane

Molecular Function: voltage-gated chloride channel activity; ATP binding; antiporter activity

Biological Process: response to mechanical stimulus; chloride transport; signal transduction; cell volume homeostasis; transmembrane transport
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 Research Articles on CLCN6    1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CLCN6 elisa kitDiseases associated with CLCN6 elisa kit
 Products by Pathway  Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Disease Name  Pubmed Publications
 Metabolic Diseases Antibodies  >4 publications with CLCN6 and Metabolic Diseases
 Congenital Abnormalities Antibodies  >1 publications with CLCN6 and Congenital Abnormalities
 Fibrosis Antibodies  >1 publications with CLCN6 and Fibrosis
 Heart Diseases Antibodies  >1 publications with CLCN6 and Heart Diseases
 Abnormalities, Multiple Antibodies  >1 publications with CLCN6 and Abnormalities, Multiple
Organs/Tissues associated with CLCN6 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with CLCN6 and Blood
 Brain Antibodies  >6 publications with CLCN6 and Brain
 Kidney Antibodies  >5 publications with CLCN6 and Kidney
 Muscle Antibodies  >3 publications with CLCN6 and Muscle
 Lung Antibodies  >3 publications with CLCN6 and Lung
 Embryonic Tissue Antibodies  >2 publications with CLCN6 and Embryonic Tissue
 Pancreas Antibodies  >2 publications with CLCN6 and Pancreas
 Testis Antibodies  >2 publications with CLCN6 and Testis
 Heart Antibodies  >2 publications with CLCN6 and Heart
 Eye Antibodies  >1 publications with CLCN6 and Eye
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