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CLDN19 elisa kit :: Canine Claudin-19 (CLDN19) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7205160 CLDN19 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Claudin-19 (CLDN19), ELISA Kit

 Also Known As   

Canine Claudin-19 (CLDN19) ELISA Kit

 Product Gene Name   

CLDN19 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    610036
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CLDN19 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CLDN19 purchase    MBS7205160 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Claudin-19 (CLDN19) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CLDN19. The ELISA analytical biochemical technique of the MBS7205160 kit is based on CLDN19 antibody-CLDN19 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLDN19 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLDN19. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CLDN19 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for CLDN19. It may not necessarily be applicable to this product.
 NCBI GI #    297515502
 NCBI GeneID    149461
 NCBI Accession #    NP_001172046.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001185117.1 [Other Products]
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 UniProt Secondary Accession #    Q5QT57; Q8N8X0; B7Z5I2; F5H5P9 [Other Products]
 UniProt Related Accession #    Q8N6F1 [Other Products]
 Molecular Weight    22,721 Da [Similar Products]
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 NCBI Official Full Name    claudin-19 isoform c
 NCBI Official Synonym Full Names    claudin 19
 NCBI Official Symbol    CLDN19 [Similar Products]
 NCBI Official Synonym Symbols   
HOMG5
[Similar Products]
 NCBI Protein Information    claudin-19
 UniProt Protein Name    Claudin-19
 Protein Family    Claudin
 UniProt Gene Name    CLDN19 [Similar Products]
 UniProt Entry Name    CLD19_HUMAN
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 NCBI Summary for CLDN19    The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
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 UniProt Comments for CLDN19    Claudin-19: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Defects in CLDN19 are the cause of hypomagnesemia renal with ocular involvement (HOMG5). HOMG5 is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. The renal phenotype is virtually undistinguishable from that of patients with HOMG3 with proven CLDN16 mutations. Belongs to the claudin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: apical junction complex; tight junction; basolateral plasma membrane; cytoplasm; integral to membrane; nucleus

Molecular Function: identical protein binding; structural molecule activity

Biological Process: apical junction assembly; visual perception; response to stimulus; action potential propagation; calcium-independent cell-cell adhesion

Disease: Hypomagnesemia 5, Renal, With Ocular Involvement
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 Research Articles on CLDN19    1. patients with CLDN19 mutations have a high risk of progression to chronic renal disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CLDN19 elisa kitPathways associated with CLDN19 elisa kit
 Reference Product  PubMed Publications
 CLDN16 elisa kit  >8 publications with CLDN19 and CLDN16
 TJP1 elisa kit  >2 publications with CLDN19 and TJP1
 CLDN18 elisa kit  >2 publications with CLDN19 and CLDN18
 CLDN10 elisa kit  >1 publications with CLDN19 and CLDN10
 TJP2 elisa kit  >1 publications with CLDN19 and TJP2
 OCLN elisa kit  >1 publications with CLDN19 and OCLN
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Tight Junction Pathway antibodies  Tight Junction Pathway Diagram
Diseases associated with CLDN19 elisa kitOrgans/Tissues associated with CLDN19 elisa kit
 Disease Name  Pubmed Publications
 Eye Abnormalities Antibodies  >2 publications with CLDN19 and Eye Abnormalities
 Hypomagnesemia 5, Renal, with Ocular Involvement Antibodies  >2 publications with CLDN19 and Hypomagnesemia 5, Renal, with Ocular Involvement
 Edema Antibodies  >1 publications with CLDN19 and Edema
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >15 publications with CLDN19 and Kidney
 Eye Antibodies  >6 publications with CLDN19 and Eye
 Brain Antibodies  >1 publications with CLDN19 and Brain
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