NP_005853.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
140,090 Da
NCBI Official Full Name
cohesin subunit SA-1
NCBI Official Synonym Full Names
stromal antigen 1
NCBI Official Synonym Symbols
NCBI Protein Information
cohesin subunit SA-1; SCC3 homolog 1; nuclear protein stromal antigen 1
UniProt Protein Name
Cohesin subunit SA-1
UniProt Synonym Protein Names
SCC3 homolog 1; Stromal antigen 1
UniProt Synonym Gene Names
UniProt Entry Name
STAG1_HUMAN
NCBI Summary for STAG1
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
UniProt Comments for STAG1
STAG1: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Belongs to the SCC3 family.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 3q22.3
Cellular Component: nucleoplasm; chromosome; nucleus; cytosol; chromatin; chromosome, pericentric region
Molecular Function: protein binding; chromatin binding
Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
Research Articles on STAG1
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Products associated with STAG1 elisa kit
Pathways associated with STAG1 elisa kit
Diseases associated with STAG1 elisa kit
Organs/Tissues associated with STAG1 elisa kit
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