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CNKSR2 elisa kit :: Canine Connector enhancer of kinase suppressor of ras 2 (CNKSR2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7247639 CNKSR2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Connector enhancer of kinase suppressor of ras 2 (CNKSR2), ELISA Kit

 Also Known As   

Canine Connector enhancer of kinase suppressor of ras 2 (CNKSR2) ELISA Kit

 Product Gene Name   

CNKSR2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    300724
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CNKSR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CNKSR2 purchase    MBS7247639 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Connector enhancer of kinase suppressor of ras 2 (CNKSR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CNKSR2. The ELISA analytical biochemical technique of the MBS7247639 kit is based on CNKSR2 antibody-CNKSR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CNKSR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CNKSR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CNKSR2 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for CNKSR2. It may not necessarily be applicable to this product.
 NCBI GI #    223460078
 NCBI GeneID    22866
 NCBI Accession #    AAI36290.1 [Other Products]
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 UniProt Secondary Accession #    O94976; Q5JPK4; Q5JPN0; Q8WXI1; B4DGR4; B7ZLJ1; B9EG83; E7ESA4 [Other Products]
 UniProt Related Accession #    Q8WXI2 [Other Products]
 Molecular Weight    113,914 Da
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 NCBI Official Full Name    Connector enhancer of kinase suppressor of Ras 2
 NCBI Official Synonym Full Names    connector enhancer of kinase suppressor of Ras 2
 NCBI Official Symbol    CNKSR2 [Similar Products]
 NCBI Official Synonym Symbols   
CNK2; KSR2; MAGUIN
[Similar Products]
 NCBI Protein Information    connector enhancer of kinase suppressor of ras 2; CNK homolog protein 2; connector enhancer of KSR2; connector enhancer of KSR 2; membrane-associated guanylate kinase-interacting protein
 UniProt Protein Name    Connector enhancer of kinase suppressor of ras 2
 UniProt Synonym Protein Names   
CNK homolog protein 2; CNK2
 Protein Family    Connector enhancer of kinase suppressor of ras
 UniProt Gene Name    CNKSR2 [Similar Products]
 UniProt Synonym Gene Names    CNK2; KIAA0902; KSR2; Connector enhancer of KSR 2; CNK2 [Similar Products]
 UniProt Entry Name    CNKR2_HUMAN
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 NCBI Summary for CNKSR2    This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
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 UniProt Comments for CNKSR2    CNKSR2: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: Xp22.12

Cellular Component: Golgi apparatus; postsynaptic membrane; neuron projection; cell soma; plasma membrane

Molecular Function: identical protein binding

Biological Process: regulation of signal transduction
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 Research Articles on CNKSR2    1. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CNKSR2 elisa kitDiseases associated with CNKSR2 elisa kit
 Reference Product  PubMed Publications
 HRAS elisa kit  >1 publications with CNKSR2 and HRAS
 LRRC7 elisa kit  >1 publications with CNKSR2 and LRRC7
 RALA elisa kit  >1 publications with CNKSR2 and RALA
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with CNKSR2 and Necrosis
 Intestinal Neoplasms Antibodies  >1 publications with CNKSR2 and Intestinal Neoplasms
 Heart Diseases Antibodies  >1 publications with CNKSR2 and Heart Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with CNKSR2 and Neurobehavioral Manifestations
 Brain Diseases Antibodies  >1 publications with CNKSR2 and Brain Diseases
Organs/Tissues associated with CNKSR2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >5 publications with CNKSR2 and Nerve
 Brain Antibodies  >5 publications with CNKSR2 and Brain
 Eye Antibodies  >2 publications with CNKSR2 and Eye
 Blood Antibodies  >2 publications with CNKSR2 and Blood
 Lung Antibodies  >1 publications with CNKSR2 and Lung
 Embryonic Tissue Antibodies  >1 publications with CNKSR2 and Embryonic Tissue
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