NP_001138508.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
83,136 Da
NCBI Official Full Name
conserved oligomeric Golgi complex subunit 2 isoform 2
NCBI Official Synonym Full Names
component of oligomeric golgi complex 2
NCBI Official Synonym Symbols
NCBI Protein Information
conserved oligomeric Golgi complex subunit 2; COG complex subunit 2; conserved oligomeric Golgi complex protein 2; brefeldin A-sensitive, peripheral Golgi protein; low density lipoprotein receptor defect C complementing; low density lipoprotein receptor defect C-complementing protein
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 2
UniProt Synonym Protein Names
Component of oligomeric Golgi complex 2; Low density lipoprotein receptor defect C-complementing protein
UniProt Synonym Gene Names
UniProt Entry Name
COG2_HUMAN
NCBI Summary for COG2
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2009]
UniProt Comments for COG2
COG2: Required for normal Golgi morphology and function. Belongs to the COG2 family. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 1q42.2
Cellular Component: Golgi membrane; Golgi stack; Golgi transport complex; cytosol
Molecular Function: protein binding; protein complex binding; protein transporter activity
Biological Process: intra-Golgi vesicle-mediated transport; intracellular protein transport; oligosaccharide biosynthetic process; protein amino acid glycosylation; Golgi organization and biogenesis
Research Articles on COG2
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Products associated with COG2 elisa kit
Diseases associated with COG2 elisa kit
Organs/Tissues associated with COG2 elisa kit
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