NP_004051.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cyclin-G1
NCBI Official Synonym Full Names
cyclin G1
NCBI Official Synonym Symbols
NCBI Protein Information
cyclin-G1
UniProt Protein Name
Cyclin-G1
UniProt Synonym Gene Names
UniProt Entry Name
CCNG1_HUMAN
NCBI Summary for CCNG1
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for CCNG1
CCNG1: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. Belongs to the cyclin family. Cyclin G subfamily.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 5q32-q34
Cellular Component: cell soma; perinuclear region of cytoplasm; dendrite; nucleus
Molecular Function: protein domain specific binding; protein binding
Biological Process: mitosis; cell division; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of cyclin-dependent protein kinase activity; brain development; response to organic nitrogen; cell growth; syncytium formation; negative regulation of apoptosis
Research Articles on CCNG1
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Products associated with CCNG1 elisa kit
Pathways associated with CCNG1 elisa kit
Diseases associated with CCNG1 elisa kit
Organs/Tissues associated with CCNG1 elisa kit
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