AAB18912.1
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UniProt Secondary Accession #
Molecular Weight
73,787 Da
NCBI Official Full Name
H-cadherin
UniProt Protein Name
Cadherin-13
UniProt Synonym Protein Names
Heart cadherin; H-cadherin; P105; Truncated cadherin; T-cad; T-cadherin
UniProt Synonym Gene Names
UniProt Entry Name
CAD13_HUMAN
UniProt Comments for CDH13
CDH13: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor; Cell adhesion
Chromosomal Location of Human Ortholog: 16q23.3
Cellular Component: caveola; cytoplasm; extracellular space; focal adhesion; neuron projection; plasma membrane
Molecular Function: adiponectin binding; cadherin binding; low-density lipoprotein binding
Biological Process: calcium-dependent cell-cell adhesion; endothelial cell migration; homophilic cell adhesion; keratinocyte proliferation; lamellipodium biogenesis; localization within membrane; low density lipoprotein mediated signaling; negative regulation of cell adhesion; negative regulation of cell proliferation; positive regulation of calcium-mediated signaling; positive regulation of cell migration; positive regulation of cell-matrix adhesion; positive regulation of endothelial cell proliferation; positive regulation of positive chemotaxis; positive regulation of smooth muscle cell proliferation; positive regulation of transcription from RNA polymerase II promoter; Rac protein signal transduction; regulation of endocytosis; regulation of epidermal growth factor receptor signaling pathway; Rho protein signal transduction; sprouting angiogenesis
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