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HMG1 elisa kit :: Canine High Mobility Group Protein 1 (HMG1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9308917 HMG1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

High Mobility Group Protein 1 (HMG1), ELISA Kit

★Popular Item★
 Also Known As   

Canine High Mobility Group Protein 1 (HMG1) ELISA Kit

 Product Gene Name   

HMG1 elisa kit

[Similar Products]
 Product Synonym Gene Name    HMGB1; HMG3; SBP1; Sulfoglucuronyl Carbohydrate Binding Protein; Amphoterin; [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 13; NC_000013.11 (30458740..30465944, complement). Location: 13q12
 OMIM    163905
 3D Structure    ModBase 3D Structure for P09429
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 Species Reactivity    Canine
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    6.25 ng/ml - 200 ng/ml
 Sensitivity    1.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HMG1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HMG1 purchase    MBS9308917 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the High Mobility Group Protein 1 (HMG1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25 ng/ml - 200 ng/ml in biological research samples containing HMG1, with an estimated sensitivity of 1.0 ng/ml. The ELISA analytical biochemical technique of the MBS9308917 kit is based on HMG1 antibody-HMG1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HMG1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HMG1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HMG1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HMG1 (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9308917. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HMG1. It may not necessarily be applicable to this product.
 NCBI GI #    4504425
 NCBI GeneID    3146
 NCBI Accession #    NP_002119.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002128.4 [Other Products]
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 UniProt Primary Accession #    P09429 [Other Products]
 UniProt Secondary Accession #    Q14321; Q5T7C3; Q6IBE1; A5D8W9 [Other Products]
 UniProt Related Accession #    P09429 [Other Products]
 Molecular Weight    24,894 Da
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 NCBI Official Full Name    high mobility group protein B1
 NCBI Official Synonym Full Names    high mobility group box 1
 NCBI Official Symbol    HMGB1 [Similar Products]
 NCBI Official Synonym Symbols   
HMG1; HMG3; SBP-1
[Similar Products]
 NCBI Protein Information    high mobility group protein B1; HMG-1; Amphoterin; high-mobility group box 1; high mobility group protein 1; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1
 UniProt Protein Name    High mobility group protein B1
 UniProt Synonym Protein Names   
High mobility group protein 1
 Protein Family    High mobility group protein
 UniProt Gene Name    HMGB1 [Similar Products]
 UniProt Synonym Gene Names    HMG1; HMG-1 [Similar Products]
 UniProt Entry Name    HMGB1_HUMAN
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 UniProt Comments for HMG1    HMGB1: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells. Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2. Belongs to the HMGB family.

Protein type: Nuclear receptor co-regulator; DNA repair, damage

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: nucleoplasm; extracellular space; cell surface; transcriptional repressor complex; extracellular region; condensed chromosome; nucleus

Molecular Function: protein binding; RAGE receptor binding; double-stranded DNA binding; damaged DNA binding; cytokine activity; chromatin binding; transcription factor binding; DNA bending activity; transcription factor activity; single-stranded DNA binding; chemoattractant activity

Biological Process: negative regulation of transcriptional preinitiation complex assembly; DNA topological change; V(D)J recombination; positive regulation of apoptosis; apoptosis; positive regulation of caspase activity; base-excision repair, DNA ligation; negative regulation of transcription from RNA polymerase II promoter; DNA recombination; regulation of transcription from RNA polymerase II promoter; chromatin remodeling; myeloid dendritic cell activation; inflammatory response to antigenic stimulus; positive chemotaxis; DNA ligation during DNA repair; dendritic cell chemotaxis; innate immune response; positive regulation of transcription from RNA polymerase II promoter; DNA fragmentation during apoptosis; neurite development; positive regulation of DNA binding; cell structure disassembly during apoptosis
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 Research Articles on HMG1    1. Patients with 1176G/G genotype of HMGB1 gene are more likely to have a progressive status in chronic hepatitis B infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HMG1 elisa kitPathways associated with HMG1 elisa kit
 Reference Product  PubMed Publications
 TNF elisa kit  >388 publications with HMG1 and TNF
 TLR4 elisa kit  >282 publications with HMG1 and TLR4
 TP53 elisa kit  >6 publications with HMG1 and TP53
 AGER elisa kit  >3 publications with HMG1 and AGER
 DIF elisa kit  >2 publications with HMG1 and DIF
 PLAT elisa kit  >1 publications with HMG1 and PLAT
 Products by Pathway  Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of DNA Fragmentation Factor Pathway antibodies  Activation Of DNA Fragmentation Factor Pathway Diagram
 Advanced Glycosylation Endproduct Receptor Signaling Pathway antibodies  Advanced Glycosylation Endproduct Receptor Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Induced DNA Fragmentation Pathway antibodies  Apoptosis Induced DNA Fragmentation Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Base Excision Repair Pathway antibodies  Base Excision Repair Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway antibodies  DEx/H-box Helicases Activate Type I IFN And Inflammatory Cytokines Production Pathway Diagram
Diseases associated with HMG1 elisa kitOrgans/Tissues associated with HMG1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1107 publications with HMG1 and Inflammation
 Necrosis Antibodies  >634 publications with HMG1 and Necrosis
 Sepsis Antibodies  >433 publications with HMG1 and Sepsis
 Neoplasms Antibodies  >420 publications with HMG1 and Neoplasms
 Disease Models, Animal Antibodies  >317 publications with HMG1 and Disease Models, Animal
 Lung Diseases Antibodies  >179 publications with HMG1 and Lung Diseases
 Liver Diseases Antibodies  >133 publications with HMG1 and Liver Diseases
 Heart Diseases Antibodies  >96 publications with HMG1 and Heart Diseases
 Myocardial Ischemia Antibodies  >84 publications with HMG1 and Myocardial Ischemia
 Atherosclerosis Antibodies  >70 publications with HMG1 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >950 publications with HMG1 and Blood
 Liver Antibodies  >339 publications with HMG1 and Liver
 Lung Antibodies  >304 publications with HMG1 and Lung
 Brain Antibodies  >252 publications with HMG1 and Brain
 Vascular Antibodies  >245 publications with HMG1 and Vascular
 Muscle Antibodies  >141 publications with HMG1 and Muscle
 Heart Antibodies  >128 publications with HMG1 and Heart
 Kidney Antibodies  >125 publications with HMG1 and Kidney
 Bone Antibodies  >102 publications with HMG1 and Bone
 Nerve Antibodies  >95 publications with HMG1 and Nerve
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