NP_001161077.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
31,059 Da
NCBI Official Full Name
kallikrein-11 isoform 3
NCBI Official Synonym Full Names
kallikrein-related peptidase 11
NCBI Official Synonym Symbols
NCBI Protein Information
kallikrein-11; hK11; hippostasin; kallikrein 11; serine protease 20; trypsin-like protease
UniProt Protein Name
Kallikrein-11
UniProt Synonym Protein Names
Hippostasin; Serine protease 20; Trypsin-like protease
UniProt Synonym Gene Names
UniProt Entry Name
KLK11_HUMAN
NCBI Summary for KLK11
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009]
UniProt Comments for KLK11
KLK11: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; EC 3.4.21.-; Protease
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: Golgi apparatus; extracellular space
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
Research Articles on KLK11
Precautions
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Products associated with KLK11 elisa kit
Diseases associated with KLK11 elisa kit
Organs/Tissues associated with KLK11 elisa kit
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