AAD14960.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,345 Da
NCBI Official Full Name
luteinizing hormone beta subunit (LHbeta), partial
NCBI Official Synonym Full Names
luteinizing hormone beta polypeptide
NCBI Protein Information
lutropin subunit beta; LSH-beta; lutropin beta chain; luteinizing hormone beta subunit; interstitial cell stimulating hormone, beta chain
UniProt Protein Name
Lutropin subunit beta
UniProt Synonym Protein Names
Luteinizing hormone subunit beta
UniProt Synonym Gene Names
UniProt Entry Name
LSHB_HUMAN
NCBI Summary for LH
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
UniProt Comments for LH
LHB: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Defects in LHB are a cause of hypogonadism LHB-related (HGON-LHB). Hypogonadism is characterized by infertility and pseudohermaphroditism. Belongs to the glycoprotein hormones subunit beta family.
Protein type: Secreted, signal peptide; Secreted; Hormone
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: extracellular region
Molecular Function: hormone activity; receptor binding
Biological Process: progesterone biosynthetic process; cellular protein metabolic process; cell-cell signaling; male gonad development; peptide hormone processing; signal transduction
Disease: Fertile Eunuch Syndrome
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Products associated with LH elisa kit
Pathways associated with LH elisa kit
Organs/Tissues associated with LH elisa kit
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