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OPN1MW elisa kit :: Canine Medium-wave-sensitive opsin 1 (OPN1MW) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7222287 OPN1MW elisa kit
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Medium-wave-sensitive opsin 1 (OPN1MW), ELISA Kit

 Also Known As   

Canine Medium-wave-sensitive opsin 1 (OPN1MW) ELISA Kit

 Product Gene Name   

OPN1MW elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    303800
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of OPN1MW elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OPN1MW purchase    MBS7222287 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Medium-wave-sensitive opsin 1 (OPN1MW) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OPN1MW. The ELISA analytical biochemical technique of the MBS7222287 kit is based on OPN1MW antibody-OPN1MW antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OPN1MW antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OPN1MW. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for OPN1MW. It may not necessarily be applicable to this product.
 NCBI GI #    4503965
 NCBI GeneID    2652
 NCBI Accession #    NP_000504.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000513.2 [Other Products]
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 UniProt Related Accession #    P04001 [Other Products]
 Molecular Weight    40,584 Da
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 NCBI Official Full Name    medium-wave-sensitive opsin 1
 NCBI Official Synonym Full Names    opsin 1 (cone pigments), medium-wave-sensitive
 NCBI Official Symbol    OPN1MW [Similar Products]
 NCBI Official Synonym Symbols   
CBD; GCP; GOP; CBBM; COD5; OPN1MW1
[Similar Products]
 NCBI Protein Information    medium-wave-sensitive opsin 1; green cone pigment; green-sensitive opsin; photopigment apoprotein; cone dystrophy 5 (X-linked); green cone photoreceptor pigment
 UniProt Protein Name    Medium-wave-sensitive opsin 1
 UniProt Synonym Protein Names   
Green cone photoreceptor pigment; Green-sensitive opsin; GOP
 Protein Family    Medium-wave-sensitive opsin
 UniProt Gene Name    OPN1MW [Similar Products]
 UniProt Synonym Gene Names    GCP
OPN1MW2; GOP
[Similar Products]
 UniProt Entry Name    OPSG_HUMAN
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 NCBI Summary for OPN1MW    This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness. [provided by RefSeq, Mar 2009]
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 UniProt Comments for OPN1MW    OPN1MW: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Defects in OPN1MW are the cause of partial colorblindness deutan series (CBD); also known as deuteranopia. Defects in OPN1MW are a cause of blue cone monochromacy (BCM). A rare X-linked congenital stationary cone dysfunction syndrome characterized by the absence of functional long wavelength-sensitive and medium wavelength-sensitive cones in the retina. Color discrimination is severely impaired from birth, and vision is derived from the remaining preserved blue (S) cones and rod photoreceptors. BCM typically presents with reduced visual acuity, pendular nystagmus, and photophobia. Patients often have myopia. Defects in OPN1MW are a cause of cone dystrophy type 5 (COD5). A X-linked cone dystrophy. Cone dystrophies are retinal dystrophies characterized by progressive degeneration of the cone photoreceptors with preservation of rod function, as indicated by electroretinogram. However, some rod involvement may be present in some cone dystrophies, particularly at late stage. Affected individuals suffer from photophobia, loss of visual acuity, color vision and central visual field. Another sign is the absence of macular lesions for many years. Cone dystrophies are distinguished from the cone-rod dystrophies in which some loss of peripheral vision also occurs. Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Protein type: GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; photoreceptor activity

Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; phototransduction, visible light; visual perception; retinoid metabolic process; protein-chromophore linkage

Disease: Blue Cone Monochromacy; Colorblindness, Partial, Deutan Series
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 Research Articles on OPN1MW    1. Identification of one single red-green OPN1LW/MW hybrid gene harboring a point mutation that associates with blue cone monochromatism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OPN1MW elisa kitPathways associated with OPN1MW elisa kit
 Reference Product  PubMed Publications
 PDE6C elisa kit  >1 publications with OPN1MW and PDE6C
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Diseases Associated With Visual Transduction Pathway antibodies  Diseases Associated With Visual Transduction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Opsins Pathway antibodies  Opsins Pathway Diagram
 Retinoid Cycle Disease Events Pathway antibodies  Retinoid Cycle Disease Events Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with OPN1MW elisa kitOrgans/Tissues associated with OPN1MW elisa kit
 Disease Name  Pubmed Publications
 Blue cone monochromatism Antibodies  >1 publications with OPN1MW and Blue cone monochromatism
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >15 publications with OPN1MW and Eye
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