NP_001137306.1
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NCBI GenBank Nucleotide #
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UniProt Related Accession #
Molecular Weight
33,648 Da
NCBI Official Full Name
metabotropic glutamate receptor 5 isoform b
NCBI Official Synonym Full Names
glutamate receptor, metabotropic 5
NCBI Official Synonym Symbols
Glu5R; Gprc1e; mGluR5; mGluR5b; AI850523; 6430542K11Rik [Similar Products]
NCBI Protein Information
metabotropic glutamate receptor 5; G protein-coupled receptor GRM5; metabotropic glutamate receptor type 5; metabotropic glutamate receptor subtype 5b; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor, family C, group 1, member E
UniProt Protein Name
Metabotropic glutamate receptor 5
UniProt Synonym Gene Names
UniProt Entry Name
GRM5_MOUSE
UniProt Comments for GRM5
mGluR5: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Belongs to the G-protein coupled receptor 3 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 3; Receptor, GPCR
Cellular Component: neuron projection; membrane; integral to plasma membrane; postsynaptic density; cytoplasm; integral to membrane; dendritic spine; plasma membrane; dendritic shaft
Molecular Function: G-protein coupled receptor activity; signal transducer activity; protein binding; PLC activating metabotropic glutamate receptor activity; glutamate receptor activity; A2A adenosine receptor binding
Biological Process: regulation of long-term neuronal synaptic plasticity; desensitization of G-protein coupled receptor protein signaling pathway; regulation of synaptic transmission, glutamatergic; locomotory behavior; learning; signal transduction; protein amino acid phosphorylation; positive regulation of long-term neuronal synaptic plasticity; G-protein coupled receptor protein signaling pathway; synaptic transmission; negative regulation of locomotion; regulation of transcription, DNA-dependent; metabotropic glutamate receptor, phospholipase C activating pathway; protein kinase C activation; metabotropic glutamate receptor signaling pathway; activation of MAPKKK activity; cognition
Research Articles on GRM5
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Pathways associated with GRM5 elisa kit
Diseases associated with GRM5 elisa kit
Organs/Tissues associated with GRM5 elisa kit
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