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PRSS1 elisa kit :: Canine Protease, Serine 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS010486 PRSS1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protease, Serine 1 (PRSS1), ELISA Kit

 Also Known As   

Canine Protease, Serine 1 ELISA Kit

 Product Gene Name   

PRSS1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 7; NC_000007.13 (142457319..142460927). Location: 7q34
 OMIM    167800
 3D Structure    ModBase 3D Structure for P07477
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 Species Reactivity    Canine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PRSS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PRSS1 purchase    MBS010486 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protease, Serine 1 (PRSS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PRSS1. The ELISA analytical biochemical technique of the MBS010486 kit is based on PRSS1 antibody-PRSS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRSS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRSS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PRSS1. It may not necessarily be applicable to this product.
 NCBI GI #    74355190
 NCBI GeneID    5644
 NCBI Accession #    AAI03999.1 [Other Products]
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 UniProt Primary Accession #    P07477 [Other Products]
 UniProt Secondary Accession #    Q5NV57; Q7M4N3; Q7M4N4; Q92955; Q9HAN4; Q9HAN5; Q9HAN6; Q9HAN7; A1A509; A6NJ71; B2R5I5 [Other Products]
 UniProt Related Accession #    P07477 [Other Products]
 Molecular Weight    26,558 Da
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 NCBI Official Full Name    PRSS1 protein
 NCBI Official Synonym Full Names    protease, serine, 1 (trypsin 1)
 NCBI Official Symbol    PRSS1 [Similar Products]
 NCBI Official Synonym Symbols   
TRP1; TRY1; TRY4; TRYP1
[Similar Products]
 NCBI Protein Information    trypsin-1; beta-trypsin; trypsinogen 1; trypsinogen A; digestive zymogen; cationic trypsinogen; nonfunctional trypsin 1
 UniProt Protein Name    Trypsin-1
 UniProt Synonym Protein Names   
Beta-trypsin; Cationic trypsinogen; Serine protease 1; Trypsin I
 Protein Family    Anionic trypsin
 UniProt Gene Name    PRSS1 [Similar Products]
 UniProt Synonym Gene Names    TRP1; TRY1; TRYP1 [Similar Products]
 UniProt Entry Name    TRY1_HUMAN
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 NCBI Summary for PRSS1    This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PRSS1    trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family.

Protein type: Protease; EC 3.4.21.4; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: extracellular region

Molecular Function: serine-type endopeptidase activity; metal ion binding

Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; vitamin metabolic process; cobalamin metabolic process; digestion; proteolysis; water-soluble vitamin metabolic process

Disease: Trypsinogen Deficiency; Pancreatitis, Hereditary
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 Research Articles on PRSS1    1. Case Report: suggest involvement of PRSS1 mutations in familial solid pseudopapillary pancreatic tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PRSS1 elisa kitDiseases associated with PRSS1 elisa kit
 Products by Pathway  Pathway Diagram
 Activation Of Matrix Metalloproteinases Pathway antibodies  Activation Of Matrix Metalloproteinases Pathway Diagram
 Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway antibodies  Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway Diagram
 Degradation Of The Extracellular Matrix Pathway antibodies  Degradation Of The Extracellular Matrix Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Disease Name  Pubmed Publications
 Pancreatitis Antibodies  >200 publications with PRSS1 and Pancreatitis
 Pancreatitis, Chronic Antibodies  >157 publications with PRSS1 and Pancreatitis, Chronic
 Hereditary pancreatitis Antibodies  >88 publications with PRSS1 and Hereditary pancreatitis
 Fibrosis Antibodies  >85 publications with PRSS1 and Fibrosis
 Neoplasms Antibodies  >50 publications with PRSS1 and Neoplasms
 Pancreatic Neoplasms Antibodies  >38 publications with PRSS1 and Pancreatic Neoplasms
 Inflammation Antibodies  >18 publications with PRSS1 and Inflammation
 Carcinoma Antibodies  >16 publications with PRSS1 and Carcinoma
 Immune System Diseases Antibodies  >10 publications with PRSS1 and Immune System Diseases
 Gastrointestinal Diseases Antibodies  >9 publications with PRSS1 and Gastrointestinal Diseases
Organs/Tissues associated with PRSS1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >79 publications with PRSS1 and Pancreas
 Liver Antibodies  >9 publications with PRSS1 and Liver
 Muscle Antibodies  >2 publications with PRSS1 and Muscle
 Heart Antibodies  >1 publications with PRSS1 and Heart
 Testis Antibodies  >1 publications with PRSS1 and Testis
 Prostate Antibodies  >1 publications with PRSS1 and Prostate
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