Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow RGS4 rightarrow Canine RGS4  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • c-Abl (Ab-245) Antibody
 • Gastrin-Reliasing Peptide (GRP) ELISA Kit
 • Glucoprotein 210 Gp210 ELISA Kit
 • Actinin Alpha 2 (ACTN2) ELISA Kit
 • Hyperglycosylated Chorionic Gonadotropin (HCG-H) ELISA Kit
 • Stromal Cell Derived Factor 1 (SDF1) ELISA Kit
 • Collagen Type II (COL2) ELISA Kit
 • 4-Hydroxynonenal (4-HNE) ELISA Kit
 • Nuclear Antibody (ANA) ELISA Kit
 • Hexokinase 3 (HK3) ELISA Kit
 • Transmembrane Emp24 Protein Transport Domain Containing 1 (T... ELISA Kit
 • Chemokine C-C Motif Ligand 5 (CCL-5) ELISA Kit
 • L-Phenylalanine (LPA) ELISA Kit
 • Sex Hormone Binding Globulin (SHBG) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

RGS4 elisa kit :: Canine Regulator of G Protein Signaling 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS044862 RGS4 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Regulator of G Protein Signaling 4 (RGS4), ELISA Kit

 Also Known As   

Canine Regulator of G Protein Signaling 4 ELISA Kit

 Product Gene Name   

RGS4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 1; NC_000001.10 (163038396..163046592). Location: 1q23.3
 OMIM    181500
 3D Structure    ModBase 3D Structure for P49798
Section Bar
 Species Reactivity    Canine
Section Bar
Section Bar
 Assay Type    Sandwich
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RGS4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RGS4 purchase    MBS044862 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Regulator of G Protein Signaling 4 (RGS4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RGS4. The ELISA analytical biochemical technique of the MBS044862 kit is based on RGS4 antibody-RGS4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RGS4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RGS4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RGS4. It may not necessarily be applicable to this product.
 NCBI GI #    5032039
 NCBI GeneID    5999
 NCBI Accession #    NP_005604.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005613.5 [Other Products]
Section Bar
 UniProt Primary Accession #    P49798 [Other Products]
 UniProt Secondary Accession #    A7XA56; A7XA58; A7XA59; A7YVV7; B1APZ3 [Other Products]
 UniProt Related Accession #    P49798 [Other Products]
 Molecular Weight    23,256 Da
Table BarTOPTable Bar
 NCBI Official Full Name    regulator of G-protein signaling 4 isoform 2
 NCBI Official Synonym Full Names    regulator of G-protein signaling 4
 NCBI Official Symbol    RGS4 [Similar Products]
 NCBI Official Synonym Symbols   
RGP4; SCZD9
[Similar Products]
 NCBI Protein Information    regulator of G-protein signaling 4; schizophrenia disorder 9
 UniProt Protein Name    Regulator of G-protein signaling 4
 Protein Family    Regulator of G-protein signaling
 UniProt Gene Name    RGS4 [Similar Products]
 UniProt Synonym Gene Names    RGP4; RGS4 [Similar Products]
 UniProt Entry Name    RGS4_HUMAN
Section Bar
 NCBI Summary for RGS4    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for RGS4    RGS4: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein. Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs, RGS; GAPs

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: protein complex; cytoplasm; plasma membrane; cytosol

Molecular Function: calmodulin binding; G-protein alpha-subunit binding; GTPase activator activity

Biological Process: regulation of G-protein coupled receptor protein signaling pathway; positive regulation of GTPase activity; inactivation of MAPK activity

Disease: Schizophrenia 9
Table BarTOPTable Bar
 Research Articles on RGS4    1. dramatic up-regulation of RGS4 expression in the nucleus accumbens of subjects treated with monoamine-directed antidepressants
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with RGS4 elisa kitPathways associated with RGS4 elisa kit
 Reference Product  PubMed Publications
 DRD3 elisa kit  >4 publications with RGS4 and DRD3
 ERBB3 elisa kit  >3 publications with RGS4 and ERBB3
 DRD2 elisa kit  >3 publications with RGS4 and DRD2
 GNAI2 elisa kit  >3 publications with RGS4 and GNAI2
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 G Alpha (z) Signalling Events Pathway antibodies  G Alpha (z) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
Diseases associated with RGS4 elisa kitOrgans/Tissues associated with RGS4 elisa kit
 Disease Name  Pubmed Publications
 Schizophrenia Antibodies  >97 publications with RGS4 and Schizophrenia
 Cardiovascular Diseases Antibodies  >34 publications with RGS4 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >27 publications with RGS4 and Nervous System Diseases
 Heart Diseases Antibodies  >23 publications with RGS4 and Heart Diseases
 Neoplasms Antibodies  >21 publications with RGS4 and Neoplasms
 Heart Failure Antibodies  >17 publications with RGS4 and Heart Failure
 Hypertension Antibodies  >11 publications with RGS4 and Hypertension
 Cognition Disorders Antibodies  >10 publications with RGS4 and Cognition Disorders
 Movement Disorders Antibodies  >8 publications with RGS4 and Movement Disorders
 Kidney Diseases Antibodies  >8 publications with RGS4 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >150 publications with RGS4 and Brain
 Nerve Antibodies  >36 publications with RGS4 and Nerve
 Kidney Antibodies  >31 publications with RGS4 and Kidney
 Vascular Antibodies  >26 publications with RGS4 and Vascular
 Pancreas Antibodies  >10 publications with RGS4 and Pancreas
 Lung Antibodies  >10 publications with RGS4 and Lung
 Embryonic Tissue Antibodies  >9 publications with RGS4 and Embryonic Tissue
 Intestine Antibodies  >9 publications with RGS4 and Intestine
 Eye Antibodies  >8 publications with RGS4 and Eye
 Liver Antibodies  >7 publications with RGS4 and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions