NP_068739.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Related Accession #
Molecular Weight
13,016 Da
NCBI Official Full Name
secretin preproprotein
NCBI Official Synonym Full Names
secretin
NCBI Protein Information
secretin
UniProt Protein Name
Secretin
UniProt Entry Name
SECR_HUMAN
NCBI Summary for SCT
This gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016]
UniProt Comments for SCT
SCT: Stimulates formation of NaHCO(3)-rich pancreatic juice and secretion of NaHCO(3)-rich bile and inhibits HCl production by the stomach. Belongs to the glucagon family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: extracellular region; extracellular space
Molecular Function: hormone activity; protein N-terminus binding
Biological Process: dentate gyrus development; embryonic gut development; negative regulation of neuron apoptosis; pancreatic juice secretion; positive regulation of cAMP biosynthetic process; visual learning
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with SCT elisa kit
Pathways associated with SCT elisa kit
Diseases associated with SCT elisa kit
Organs/Tissues associated with SCT elisa kit
|