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TLN elisa kit :: Canine Talin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS006386 TLN elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Talin (TLN), ELISA Kit

 Also Known As   

Canine Talin ELISA Kit

 Product Gene Name   

TLN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 9; NC_000009.11 (35697334..35732392, complement). Location: 9p13
 OMIM    186745
 3D Structure    ModBase 3D Structure for Q9Y490
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 Species Reactivity    Canine
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TLN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TLN purchase    MBS006386 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Talin (TLN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TLN. The ELISA analytical biochemical technique of the MBS006386 kit is based on TLN antibody-TLN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TLN. It may not necessarily be applicable to this product.
 NCBI GI #    6682361
 NCBI GeneID    7094
 NCBI Accession #    AAF23322.1 [Other Products]
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 UniProt Primary Accession #    Q9Y490 [Other Products]
 UniProt Secondary Accession #    Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; A6NMY0 [Other Products]
 UniProt Related Accession #    Q9Y490 [Other Products]
 Molecular Weight    269,767 Da
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 NCBI Official Full Name    talin
 NCBI Official Synonym Full Names    talin 1
 NCBI Official Symbol    TLN1 [Similar Products]
 NCBI Official Synonym Symbols   
TLN; ILWEQ
[Similar Products]
 NCBI Protein Information    talin-1
 UniProt Protein Name    Talin-1
 Protein Family    Talin
 UniProt Gene Name    TLN1 [Similar Products]
 UniProt Synonym Gene Names    KIAA1027; TLN [Similar Products]
 UniProt Entry Name    TLN1_HUMAN
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 NCBI Summary for TLN    This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
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 UniProt Comments for TLN    Talin-1: a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: ruffle; cell surface; focal adhesion; cytoplasm; plasma membrane; extracellular region; microtubule organizing center; intercellular junction; cytosol

Molecular Function: actin filament binding; integrin binding; protein binding; LIM domain binding; structural constituent of cytoskeleton; insulin receptor binding; vinculin binding

Biological Process: axon guidance; intercellular junction assembly; platelet activation; unfolded protein response; cytoskeletal anchoring; platelet degranulation; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; muscle contraction; cell-substrate junction assembly; cortical actin cytoskeleton organization and biogenesis; cell motility; blood coagulation
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 Research Articles on TLN    1. Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TLN elisa kitPathways associated with TLN elisa kit
 Reference Product  PubMed Publications
 ITGB1 elisa kit  >3 publications with TLN and ITGB1
 PTK2 elisa kit  >3 publications with TLN and PTK2
 ITGB5 elisa kit  >1 publications with TLN and ITGB5
 ITGA5 elisa kit  >1 publications with TLN and ITGA5
 ITGB3 elisa kit  >1 publications with TLN and ITGB3
 Products by Pathway  Pathway Diagram
 Activation Of Chaperone Genes By XBP1(S) Pathway antibodies  Activation Of Chaperone Genes By XBP1(S) Pathway Diagram
 Activation Of Chaperones By IRE1alpha Pathway antibodies  Activation Of Chaperones By IRE1alpha Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EGF Receptor (ErbB1) Signaling Pathway antibodies  EGF Receptor (ErbB1) Signaling Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway antibodies  GRB2:SOS Provides Linkage To MAPK Signaling For Intergrins Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
Diseases associated with TLN elisa kitOrgans/Tissues associated with TLN elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >15 publications with TLN and Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with TLN and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >4 publications with TLN and Adenocarcinoma
 Breast Neoplasms Antibodies  >3 publications with TLN and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with TLN and Carcinoma, Hepatocellular
 Neoplasm Invasiveness Antibodies  >3 publications with TLN and Neoplasm Invasiveness
 Liver Diseases Antibodies  >2 publications with TLN and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with TLN and Liver Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with TLN and Cell Transformation, Neoplastic
 Prostatic Diseases Antibodies  >2 publications with TLN and Prostatic Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >12 publications with TLN and Blood
 Vascular Antibodies  >5 publications with TLN and Vascular
 Bone Antibodies  >4 publications with TLN and Bone
 Prostate Antibodies  >3 publications with TLN and Prostate
 Muscle Antibodies  >3 publications with TLN and Muscle
 Liver Antibodies  >3 publications with TLN and Liver
 Thyroid Antibodies  >2 publications with TLN and Thyroid
 Mouth Antibodies  >2 publications with TLN and Mouth
 Placenta Antibodies  >2 publications with TLN and Placenta
 Heart Antibodies  >2 publications with TLN and Heart
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