NP_001011537.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,524 Da
NCBI Official Full Name
UAP56-interacting factor isoform 2
NCBI Official Synonym Full Names
forty-two-three domain containing 1
NCBI Official Synonym Symbols
NCBI Protein Information
UAP56-interacting factor; protein 40-2-3; forty-two-three domain-containing protein 1
UniProt Protein Name
UAP56-interacting factor
UniProt Synonym Protein Names
Forty-two-three domain-containing protein 1; Protein 40-2-3
UniProt Synonym Gene Names
UniProt Entry Name
UIF_HUMAN
UniProt Comments for FYTTD1
FYTTD1: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. Belongs to the UIF family. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: nucleoplasm; nuclear speck
Molecular Function: mRNA binding; protein binding
Biological Process: mRNA export from nucleus
Research Articles on FYTTD1
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