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VCAM-1 elisa kit :: Canine Vascular Cell Adhesion Molecule 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2604176 VCAM-1 elisa kit
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vascular Cell Adhesion Molecule 1 (VCAM-1), ELISA Kit

 Also Known As   

Canine Vascular Cell Adhesion Molecule 1 (VCAM-1) ELISA Kit

 Product Gene Name   

VCAM-1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    192225
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 Species Reactivity    Canine
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of VCAM-1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VCAM-1 purchase    MBS2604176 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vascular Cell Adhesion Molecule 1 (VCAM-1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VCAM-1. The ELISA analytical biochemical technique of the MBS2604176 kit is based on VCAM-1 antibody-VCAM-1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VCAM-1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VCAM-1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for VCAM-1. It may not necessarily be applicable to this product.
 NCBI GI #    179886
 NCBI GeneID    7412
 NCBI Accession #    AAA51917.1 [Other Products]
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 UniProt Secondary Accession #    Q6NUP8; A8K6R7; B4DKS4; E9PDD1 [Other Products]
 UniProt Related Accession #    P19320 [Other Products]
 Molecular Weight    74,346 Da
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 NCBI Official Full Name    vascular cell adhesion molecule 1
 NCBI Official Synonym Full Names    vascular cell adhesion molecule 1
 NCBI Official Symbol    VCAM1 [Similar Products]
 NCBI Official Synonym Symbols   
CD106; INCAM-100
[Similar Products]
 NCBI Protein Information    vascular cell adhesion protein 1
 UniProt Protein Name    Vascular cell adhesion protein 1
 UniProt Synonym Protein Names   
INCAM-100; CD_antigen: CD106
 UniProt Gene Name    VCAM1 [Similar Products]
 UniProt Synonym Gene Names    L1CAM; V-CAM 1; VCAM-1 [Similar Products]
 UniProt Entry Name    VCAM1_HUMAN
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 NCBI Summary for VCAM-1    This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
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 UniProt Comments for VCAM-1    VCAM1: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p32-p31

Cellular Component: apical part of cell; cell surface; early endosome; endoplasmic reticulum; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; integral to membrane; microvillus; plasma membrane; podosome; sarcolemma

Molecular Function: amine oxidase activity; cell adhesion molecule binding; integrin binding

Biological Process: acute inflammatory response; aging; amine metabolic process; B cell differentiation; cell adhesion; cell-matrix adhesion; chronic inflammatory response; cytokine and chemokine mediated signaling pathway; extracellular matrix organization and biogenesis; heart development; heterophilic cell adhesion; leukocyte adhesion; leukocyte tethering or rolling; membrane to membrane docking; positive regulation of T cell proliferation; regulation of immune response; response to ethanol; response to hypoxia; response to ionizing radiation; response to lipopolysaccharide; response to nicotine; response to nutrient; response to zinc ion; viral reproduction
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 Research Articles on VCAM-1    1. neutrophils are reliant on endothelial activation for adhesion, initially via E-selectin and subsequently, by integrin-mediated binding to ICAM-1 and VCAM-1, combined with CXCL8-dependent chemotaxis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VCAM-1 elisa kitPathways associated with VCAM-1 elisa kit
 Reference Product  PubMed Publications
 ICAM1 elisa kit  >127 publications with VCAM-1 and ICAM1
 CD44 elisa kit  >16 publications with VCAM-1 and CD44
 ITGA4 elisa kit  >10 publications with VCAM-1 and ITGA4
 ITGB2 elisa kit  >6 publications with VCAM-1 and ITGB2
 ITGB1 elisa kit  >3 publications with VCAM-1 and ITGB1
 IRF1 elisa kit  >3 publications with VCAM-1 and IRF1
 SRC elisa kit  >2 publications with VCAM-1 and SRC
 ITGAD elisa kit  >1 publications with VCAM-1 and ITGAD
 Products by Pathway  Pathway Diagram
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 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 African Trypanosomiasis Pathway antibodies  African Trypanosomiasis Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cellular Roles Of Anthrax Toxin Pathway antibodies  Cellular Roles Of Anthrax Toxin Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
Diseases associated with VCAM-1 elisa kitOrgans/Tissues associated with VCAM-1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >118 publications with VCAM-1 and Inflammation
 Cardiovascular Diseases Antibodies  >73 publications with VCAM-1 and Cardiovascular Diseases
 Necrosis Antibodies  >59 publications with VCAM-1 and Necrosis
 Atherosclerosis Antibodies  >56 publications with VCAM-1 and Atherosclerosis
 Heart Diseases Antibodies  >19 publications with VCAM-1 and Heart Diseases
 Kidney Diseases Antibodies  >19 publications with VCAM-1 and Kidney Diseases
 Fibrosis Antibodies  >14 publications with VCAM-1 and Fibrosis
 Lung Diseases Antibodies  >13 publications with VCAM-1 and Lung Diseases
 Hypertension Antibodies  >13 publications with VCAM-1 and Hypertension
 Myocardial Ischemia Antibodies  >10 publications with VCAM-1 and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >249 publications with VCAM-1 and Vascular
 Blood Antibodies  >149 publications with VCAM-1 and Blood
 Heart Antibodies  >29 publications with VCAM-1 and Heart
 Brain Antibodies  >28 publications with VCAM-1 and Brain
 Kidney Antibodies  >27 publications with VCAM-1 and Kidney
 Embryonic Tissue Antibodies  >25 publications with VCAM-1 and Embryonic Tissue
 Liver Antibodies  >22 publications with VCAM-1 and Liver
 Lung Antibodies  >20 publications with VCAM-1 and Lung
 Lymph Node Antibodies  >8 publications with VCAM-1 and Lymph Node
 Skin Antibodies  >8 publications with VCAM-1 and Skin
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