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XDH elisa kit :: Canine Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XDH) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7208571 XDH elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XDH), ELISA Kit

 Also Known As   

Canine Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XDH) ELISA Kit

 Product Gene Name   

XDH elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS7208571 COA    COA PDF
 OMIM    607633
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 Species Reactivity    Canine
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of XDH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for XDH purchase    MBS7208571 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XDH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XDH. The ELISA analytical biochemical technique of the MBS7208571 kit is based on XDH antibody-XDH antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XDH antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XDH. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Sample Manual Insert of MBS7208571. Click to request current manual
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NCBI/Uniprot data below describe general gene information for XDH. It may not necessarily be applicable to this product.
 NCBI GI #    91823271
 NCBI GeneID    7498
 NCBI Accession #    NP_000370.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000379.3 [Other Products]
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 UniProt Secondary Accession #    Q16681; Q16712; Q4PJ16 [Other Products]
 UniProt Related Accession #    P47989 [Other Products]
 Molecular Weight    146,424 Da
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 NCBI Official Full Name    xanthine dehydrogenase/oxidase
 NCBI Official Synonym Full Names    xanthine dehydrogenase
 NCBI Official Symbol    XDH [Similar Products]
 NCBI Official Synonym Symbols   
XO; XOR
[Similar Products]
 NCBI Protein Information    xanthine dehydrogenase/oxidase; xanthine oxidoreductase
 UniProt Protein Name    Xanthine dehydrogenase/oxidase
 UniProt Synonym Protein Names   
Xanthine oxidoreductase; XOR
 Protein Family    Xanthine dehydrogenase
 UniProt Gene Name    XDH [Similar Products]
 UniProt Synonym Gene Names    XDHA; XD; XO; XOR [Similar Products]
 UniProt Entry Name    XDH_HUMAN
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 NCBI Summary for XDH    Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014]
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 UniProt Comments for XDH    XDH: Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro). Defects in XDH are the cause of xanthinuria type 1 (XU1). Xanthinuria is characterized by excretion of very large amounts of xanthine in the urine and a tendency to form xanthine stones. Uric acid is strikingly diminished in serum and urine. XU1 is due to isolated xanthine dehydrogenase. XU1 patients can metabolize allopurinol. Belongs to the xanthine dehydrogenase family.

Protein type: Nucleotide Metabolism - purine; EC 1.17.3.2; Secondary Metabolites Metabolism - caffeine; Xenobiotic Metabolism - drug metabolism - other enzymes; Oxidoreductase; EC 1.17.1.4

Chromosomal Location of Human Ortholog: 2p23.1

Cellular Component: extracellular space; peroxisome; cytosol

Molecular Function: molybdopterin cofactor binding; 2 iron, 2 sulfur cluster binding; UDP-N-acetylmuramate dehydrogenase activity; protein homodimerization activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors; FAD binding; electron carrier activity; iron ion binding; xanthine dehydrogenase activity; xanthine oxidase activity

Biological Process: lactation; caspase activation; xanthine catabolic process; negative regulation of protein kinase B signaling cascade; negative regulation of protein amino acid phosphorylation; negative regulation of endothelial cell differentiation; nucleobase, nucleoside and nucleotide metabolic process; negative regulation of endothelial cell proliferation; purine nucleotide catabolic process; purine base metabolic process

Disease: Xanthinuria, Type I
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 Research Articles on XDH    1. This study reveals a noncanonical molecular pathway in which, after the inhibition of cathepsin S, autophagy induces early reactive oxygen species production for oxidative DNA damage and cell death through xanthine oxidase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with XDH elisa kitPathways associated with XDH elisa kit
 Reference Product  PubMed Publications
 CAT elisa kit  >10 publications with XDH and CAT
 HPRT1 elisa kit  >4 publications with XDH and HPRT1
 AOX1 elisa kit  >3 publications with XDH and AOX1
 TPMT elisa kit  >2 publications with XDH and TPMT
 PNP elisa kit  >2 publications with XDH and PNP
 GDA elisa kit  >2 publications with XDH and GDA
 BTN1A1 elisa kit  >1 publications with XDH and BTN1A1
 Products by Pathway  Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Oxidative Stress Pathway antibodies  Oxidative Stress Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
Diseases associated with XDH elisa kitOrgans/Tissues associated with XDH elisa kit
 Disease Name  Pubmed Publications
 Ischemia Antibodies  >37 publications with XDH and Ischemia
 Reperfusion Injury Antibodies  >28 publications with XDH and Reperfusion Injury
 Cardiovascular Diseases Antibodies  >24 publications with XDH and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >22 publications with XDH and Disease Models, Animal
 Inflammation Antibodies  >18 publications with XDH and Inflammation
 Kidney Diseases Antibodies  >17 publications with XDH and Kidney Diseases
 Nervous System Diseases Antibodies  >11 publications with XDH and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >9 publications with XDH and Neoplasms, Experimental
 Necrosis Antibodies  >7 publications with XDH and Necrosis
 Hypertension Antibodies  >7 publications with XDH and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >83 publications with XDH and Liver
 Kidney Antibodies  >35 publications with XDH and Kidney
 Lung Antibodies  >21 publications with XDH and Lung
 Muscle Antibodies  >18 publications with XDH and Muscle
 Intestine Antibodies  >16 publications with XDH and Intestine
 Eye Antibodies  >11 publications with XDH and Eye
 Mammary Gland Antibodies  >7 publications with XDH and Mammary Gland
 Embryonic Tissue Antibodies  >6 publications with XDH and Embryonic Tissue
 Placenta Antibodies  >5 publications with XDH and Placenta
 Mouth Antibodies  >2 publications with XDH and Mouth
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