NP_001138356.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
41,626 Da
NCBI Official Full Name
zinc transporter 7
NCBI Official Synonym Full Names
solute carrier family 30 (zinc transporter), member 7
NCBI Protein Information
zinc transporter 7; zinc transporter ZnT-7; znt-like transporter 2; zinc transporter like 2; solute carrier family 30 member 7
UniProt Protein Name
Zinc transporter 7
UniProt Synonym Protein Names
Solute carrier family 30 member 7; Znt-like transporter 2
UniProt Synonym Gene Names
UniProt Entry Name
ZNT7_HUMAN
NCBI Summary for SLC30A7
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]
UniProt Comments for SLC30A7
SLC30A7: Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Protein type: Membrane protein, integral; Vesicle; Transporter, SLC family; Transporter; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p21.2
Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; cytoplasmic membrane-bound vesicle; cytoplasm; integral to membrane; vesicle
Molecular Function: cation transmembrane transporter activity
Biological Process: sequestering of zinc ion; cellular protein metabolic process; zinc ion transport; transmembrane transport
Research Articles on SLC30A7
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Products associated with SLC30A7 elisa kit
Pathways associated with SLC30A7 elisa kit
Diseases associated with SLC30A7 elisa kit
Organs/Tissues associated with SLC30A7 elisa kit
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