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KLK7 elisa kit :: Cat Kallikrein 7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS099308 KLK7 elisa kit
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 Product Name   

Kallikrein 7 (KLK7), ELISA Kit

 Also Known As   

Cat Kallikrein 7 ELISA Kit

 Product Gene Name   

KLK7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 19; NC_000019.9 (51479735..51487320, complement). Location: 19q13.41
 OMIM    604438
 3D Structure    ModBase 3D Structure for P49862
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 Species Reactivity    Cat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of KLK7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for KLK7 purchase    MBS099308 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Kallikrein 7 (KLK7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KLK7. The ELISA analytical biochemical technique of the MBS099308 kit is based on KLK7 antibody-KLK7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KLK7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KLK7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for KLK7. It may not necessarily be applicable to this product.
 NCBI GI #    341823646
 NCBI GeneID    5650
 NCBI Accession #    NP_001230055.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243126.1 [Other Products]
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 UniProt Primary Accession #    P49862 [Other Products]
 UniProt Secondary Accession #    Q8N5N9; Q8NFV7 [Other Products]
 UniProt Related Accession #    P49862 [Other Products]
 Molecular Weight    27,525 Da
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 NCBI Official Full Name    kallikrein-7 isoform 3
 NCBI Official Synonym Full Names    kallikrein-related peptidase 7
 NCBI Official Symbol    KLK7 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    kallikrein-7; signal protein; serine protease 6; stratum corneum chymotryptic enzyme; kallikrein 7 (chymotryptic, stratum corneum)
 UniProt Protein Name    Kallikrein-7
 UniProt Synonym Protein Names   
Serine protease 6; Stratum corneum chymotryptic enzyme
 Protein Family    Kallikrein
 UniProt Gene Name    KLK7 [Similar Products]
 UniProt Synonym Gene Names    PRSS6; SCCE; hK7; hSCCE [Similar Products]
 UniProt Entry Name    KLK7_HUMAN
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 NCBI Summary for KLK7    This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
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 UniProt Comments for KLK7    KLK7: May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted; EC; Protease

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region

Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: extracellular matrix disassembly; epidermis development; extracellular matrix organization and biogenesis; proteolysis
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 Research Articles on KLK7    1. Prochemerin processing protease converts prochemerin into active chemerinF; the activating truncation by the protease may trigger a structural C-terminal rearrangement leading to increased affinity of chemerin to chemokine-like receptor (CMKLR)1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with KLK7 elisa kitDiseases associated with KLK7 elisa kit
 Reference Product  PubMed Publications
 KLK5 elisa kit  >61 publications with KLK7 and KLK5
 KLK8 elisa kit  >24 publications with KLK7 and KLK8
 SPINK5 elisa kit  >21 publications with KLK7 and SPINK5
 KLK10 elisa kit  >13 publications with KLK7 and KLK10
 CDSN elisa kit  >7 publications with KLK7 and CDSN
 A2ML1 elisa kit  >2 publications with KLK7 and A2ML1
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >43 publications with KLK7 and Neoplasms
 Genital Neoplasms, Female Antibodies  >15 publications with KLK7 and Genital Neoplasms, Female
 Ovarian Neoplasms Antibodies  >14 publications with KLK7 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >13 publications with KLK7 and Adenocarcinoma
 Inflammation Antibodies  >11 publications with KLK7 and Inflammation
 Skin Neoplasms Antibodies  >9 publications with KLK7 and Skin Neoplasms
 Carcinoma, Squamous Cell Antibodies  >8 publications with KLK7 and Carcinoma, Squamous Cell
 Breast Neoplasms Antibodies  >8 publications with KLK7 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with KLK7 and Neoplasms, Experimental
 Hyperplasia Antibodies  >4 publications with KLK7 and Hyperplasia
Organs/Tissues associated with KLK7 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >96 publications with KLK7 and Skin
 Prostate Antibodies  >11 publications with KLK7 and Prostate
 Mouth Antibodies  >7 publications with KLK7 and Mouth
 Ovary Antibodies  >6 publications with KLK7 and Ovary
 Pancreas Antibodies  >6 publications with KLK7 and Pancreas
 Brain Antibodies  >6 publications with KLK7 and Brain
 Lung Antibodies  >4 publications with KLK7 and Lung
 Kidney Antibodies  >3 publications with KLK7 and Kidney
 Mammary Gland Antibodies  >3 publications with KLK7 and Mammary Gland
 Lymph Node Antibodies  >3 publications with KLK7 and Lymph Node
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