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OPN elisa kit :: Cat Osteopontin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS108565 OPN elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Osteopontin (OPN), ELISA Kit

 Also Known As   

Cat Osteopontin ELISA Kit

 Product Gene Name   

OPN elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 Chromosome Location    Chromosome: 4; NC_000004.11 (88896802..88904563). Location: 4q22.1
 OMIM    166490
 3D Structure    ModBase 3D Structure for P10451
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 Species Reactivity    Cat
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of OPN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for OPN purchase    MBS108565 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Osteopontin (OPN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing OPN. The ELISA analytical biochemical technique of the MBS108565 kit is based on OPN antibody-OPN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect OPN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, OPN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for OPN. It may not necessarily be applicable to this product.
 NCBI GI #    189405
 NCBI GeneID    6696
 NCBI Accession #    AAA59974.1 [Other Products]
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 UniProt Primary Accession #    P10451 [Other Products]
 UniProt Secondary Accession #    Q15681; Q15682; Q15683; Q4W597; Q567T5; Q8NBK2; Q96IZ1; B2RDA1 [Other Products]
 UniProt Related Accession #    P10451 [Other Products]
 Molecular Weight    35,423 Da
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 NCBI Official Full Name    osteopontin
 NCBI Official Synonym Full Names    secreted phosphoprotein 1
 NCBI Official Symbol    SPP1 [Similar Products]
 NCBI Official Synonym Symbols   
OPN; BNSP; BSPI; ETA-1
[Similar Products]
 NCBI Protein Information    osteopontin; uropontin; nephropontin; SPP1/CALPHA1 fusion; urinary stone protein; early T-lymphocyte activation 1; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)
 UniProt Protein Name    Osteopontin
 UniProt Synonym Protein Names   
Bone sialoprotein 1; Nephropontin; Secreted phosphoprotein 1; SPP-1; Urinary stone protein; Uropontin
 Protein Family    Osteopontin
 UniProt Gene Name    SPP1 [Similar Products]
 UniProt Synonym Gene Names    BNSP; OPN; SPP-1 [Similar Products]
 UniProt Entry Name    OSTP_HUMAN
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 NCBI Summary for OPN    The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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 UniProt Comments for OPN    osteopontin: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Belongs to the osteopontin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 4q22.1

Cellular Component: extracellular space; cell projection; perinuclear region of cytoplasm; apical part of cell; extracellular region

Molecular Function: protein binding; extracellular matrix binding; cytokine activity

Biological Process: osteoblast differentiation; extracellular matrix disassembly; neutrophil chemotaxis; extracellular matrix organization and biogenesis; response to vitamin D; response to steroid hormone stimulus; biomineral formation; negative regulation of collateral sprouting of intact axon in response to injury; positive regulation of bone resorption; decidualization; cell adhesion; inflammatory response; embryo implantation
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 Research Articles on OPN    1. The N-terminal fragment of osteopontin, rather than full-length OPN or C-terminal OPN, is associated with carotid plaque inflammation in hypertensive patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with OPN elisa kitPathways associated with OPN elisa kit
 Reference Product  PubMed Publications
 CD44 elisa kit  >112 publications with OPN and CD44
 RUNX2 elisa kit  >95 publications with OPN and RUNX2
 BMP2 elisa kit  >63 publications with OPN and BMP2
 PTH elisa kit  >38 publications with OPN and PTH
 FN1 elisa kit  >10 publications with OPN and FN1
 ITGA5 elisa kit  >3 publications with OPN and ITGA5
 ITGB1 elisa kit  >2 publications with OPN and ITGB1
 ITGAV elisa kit  >2 publications with OPN and ITGAV
 ITGB3 elisa kit  >1 publications with OPN and ITGB3
 Products by Pathway  Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with OPN elisa kitOrgans/Tissues associated with OPN elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >481 publications with OPN and Neoplasms
 Cardiovascular Diseases Antibodies  >241 publications with OPN and Cardiovascular Diseases
 Kidney Diseases Antibodies  >210 publications with OPN and Kidney Diseases
 Inflammation Antibodies  >204 publications with OPN and Inflammation
 Fibrosis Antibodies  >136 publications with OPN and Fibrosis
 Necrosis Antibodies  >110 publications with OPN and Necrosis
 Calcinosis Antibodies  >104 publications with OPN and Calcinosis
 Adenocarcinoma Antibodies  >98 publications with OPN and Adenocarcinoma
 Heart Diseases Antibodies  >92 publications with OPN and Heart Diseases
 Breast Neoplasms Antibodies  >79 publications with OPN and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >998 publications with OPN and Bone
 Blood Antibodies  >488 publications with OPN and Blood
 Kidney Antibodies  >347 publications with OPN and Kidney
 Connective Tissue Antibodies  >310 publications with OPN and Connective Tissue
 Vascular Antibodies  >309 publications with OPN and Vascular
 Muscle Antibodies  >251 publications with OPN and Muscle
 Bone Marrow Antibodies  >173 publications with OPN and Bone Marrow
 Mouth Antibodies  >159 publications with OPN and Mouth
 Heart Antibodies  >118 publications with OPN and Heart
 Liver Antibodies  >113 publications with OPN and Liver
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