AAA61153.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
84,871 Da
NCBI Official Full Name
transferrin receptor
NCBI Official Synonym Full Names
transferrin receptor (p90, CD71)
NCBI Official Synonym Symbols
T9; TR; TFR; p90; CD71; TFR1; TRFR [Similar Products]
NCBI Protein Information
transferrin receptor protein 1
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
T9; p90
UniProt Synonym Gene Names
UniProt Entry Name
TFR1_HUMAN
UniProt Comments for TFR
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Protein type: Membrane protein, integral; Receptor, misc.; Cell surface
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; plasma membrane; melanosome; vesicle; endosome; external side of plasma membrane
Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding
Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; transferrin transport; positive regulation of bone resorption; regulation of cell growth; osteoclast differentiation; transmembrane transport; regulation of cell proliferation
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Products associated with TFR elisa kit
Pathways associated with TFR elisa kit
Diseases associated with TFR elisa kit
Organs/Tissues associated with TFR elisa kit
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