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ASD elisa kit :: Cavy Androstenedione ELISA Kit

Scan QR to view Datasheet Catalog #    MBS019958 ASD elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Androstenedione (ASD), ELISA Kit

 Also Known As   

Cavy Androstenedione ELISA Kit

 Product Gene Name   

ASD elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600450
 3D Structure    ModBase 3D Structure for P52895
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 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ASD elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ASD purchase    MBS019958 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Androstenedione (ASD) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ASD. The ELISA analytical biochemical technique of the MBS019958 kit is based on ASD antibody-ASD antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ASD antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ASD. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ASD. It may not necessarily be applicable to this product.
 NCBI GI #    20532374
 NCBI GeneID    1646
 NCBI Accession #    P52895.3 [Other Products]
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 UniProt Primary Accession #    P52895 [Other Products]
 UniProt Secondary Accession #    Q14133; Q5SR16; Q7M4N1; Q96A71; A8K2N9; B4DKR9 [Other Products]
 UniProt Related Accession #    P52895 [Other Products]
 Molecular Weight    36,735 Da
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 NCBI Official Full Name    Aldo-keto reductase family 1 member C2
 NCBI Official Synonym Full Names    aldo-keto reductase family 1, member C2
 NCBI Official Symbol    AKR1C2 [Similar Products]
 NCBI Official Synonym Symbols   
DD; DD2; TDD; BABP; DDH2; HBAB; HAKRD; MCDR2; SRXY8; AKR1C-pseudo
[Similar Products]
 NCBI Protein Information    aldo-keto reductase family 1 member C2; DD-2; DD/BABP; 3-alpha-HSD3; pseudo-chlordecone reductase; type II dihydrodiol dehydrogenase; chlordecone reductase homolog HAKRD; testicular 17,20-desmolase deficiency; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III
 UniProt Protein Name    Aldo-keto reductase family 1 member C2
 UniProt Synonym Protein Names   
3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC:1.3.1.20); Type III 3-alpha-hydroxysteroid dehydrogenase (EC:1.1.1.357)
 Protein Family    Aspartate-semialdehyde dehydrogenase
 UniProt Gene Name    AKR1C2 [Similar Products]
 UniProt Synonym Gene Names    DDH2; DD-2; DD2; DD/BABP [Similar Products]
 UniProt Entry Name    AK1C2_HUMAN
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 NCBI Summary for ASD    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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 UniProt Comments for ASD    AKR1C2: Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha- DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability. Defects in AKR1C2 are a cause of 46,XY sex reversal type 8 (SRXY8). A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females. Belongs to the aldo/keto reductase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.1.1.357; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.3.1.20; Oxidoreductase

Chromosomal Location of Human Ortholog: 10p15-p14

Cellular Component: cytoplasm

Molecular Function: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; ketosteroid monooxygenase activity; bile acid binding; carboxylic acid binding; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity; aldehyde reductase activity; phenanthrene 9,10-monooxygenase activity

Biological Process: steroid metabolic process; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; epithelial cell differentiation; positive regulation of cell proliferation; digestion; progesterone metabolic process; prostaglandin metabolic process

Disease: 46,xy Sex Reversal 8
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 Research Articles on ASD    1. Significantly higher levels of SRD5A1, AKR1C2, AKR1C3, and HSD17B10 mRNA were however found in bone metastases than in non-malignant and/or malignant prostate tissue
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ASD elisa kitPathways associated with ASD elisa kit
 Reference Product  PubMed Publications
 AKR1C1 elisa kit  >90 publications with ASD and AKR1C1
 AKR1C3 elisa kit  >81 publications with ASD and AKR1C3
 SRD5A2 elisa kit  >15 publications with ASD and SRD5A2
 SRD5A1 elisa kit  >12 publications with ASD and SRD5A1
 HSD17B6 elisa kit  >1 publications with ASD and HSD17B6
 Products by Pathway  Pathway Diagram
 Benzo(a)pyrene Metabolism Pathway antibodies  Benzo(a)pyrene Metabolism Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Metabolism Of Xenobiotics By Cytochrome P450 Pathway antibodies  Metabolism Of Xenobiotics By Cytochrome P450 Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
 Steroid Hormone Biosynthesis Pathway antibodies  Steroid Hormone Biosynthesis Pathway Diagram
Diseases associated with ASD elisa kitOrgans/Tissues associated with ASD elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >60 publications with ASD and Neoplasms
 Carcinoma Antibodies  >27 publications with ASD and Carcinoma
 Adenocarcinoma Antibodies  >20 publications with ASD and Adenocarcinoma
 Breast Neoplasms Antibodies  >17 publications with ASD and Breast Neoplasms
 Cholestasis Antibodies  >15 publications with ASD and Cholestasis
 Gastrointestinal Diseases Antibodies  >13 publications with ASD and Gastrointestinal Diseases
 Liver Neoplasms Antibodies  >10 publications with ASD and Liver Neoplasms
 Hyperplasia Antibodies  >6 publications with ASD and Hyperplasia
 Lung Neoplasms Antibodies  >6 publications with ASD and Lung Neoplasms
 Fatty Liver Antibodies  >6 publications with ASD and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >102 publications with ASD and Liver
 Blood Antibodies  >20 publications with ASD and Blood
 Lung Antibodies  >13 publications with ASD and Lung
 Testis Antibodies  >8 publications with ASD and Testis
 Esophagus Antibodies  >3 publications with ASD and Esophagus
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