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CD147 elisa kit :: Cavy Cd147/Emmprin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS007610 CD147 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cd147/Emmprin, ELISA Kit

 Also Known As   

Cavy Cd147/Emmprin ELISA Kit

 Product Gene Name   

CD147 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 19; NC_000019.9 (571277..583493). Location: 19p13.3
 OMIM    109480
 3D Structure    ModBase 3D Structure for P35613
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 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD147 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD147 purchase    MBS007610 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cd147/Emmprin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CD147. The ELISA analytical biochemical technique of the MBS007610 kit is based on CD147 antibody-CD147 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD147 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD147. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CD147. It may not necessarily be applicable to this product.
 NCBI GI #    31076333
 NCBI GeneID    682
 NCBI Accession #    BAC76828.1 [Other Products]
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 UniProt Primary Accession #    P35613 [Other Products]
 UniProt Secondary Accession #    Q7Z796; Q8IZL7; A6NJW1; D3YLG5 [Other Products]
 UniProt Related Accession #    P35613 [Other Products]
 Molecular Weight    42,200 Da
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 NCBI Official Full Name    CD147
 NCBI Official Synonym Full Names    basigin (Ok blood group)
 NCBI Official Symbol    BSG [Similar Products]
 NCBI Official Synonym Symbols   
M6; OK; 5F7; TCSF; CD147; EMMPRIN
[Similar Products]
 NCBI Protein Information    basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor
 UniProt Protein Name    Basigin
 UniProt Synonym Protein Names   
5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor
 UniProt Gene Name    BSG [Similar Products]
 UniProt Synonym Gene Names    EMMPRIN; TCSF [Similar Products]
 UniProt Entry Name    BASI_HUMAN
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 NCBI Summary for CD147    The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD147    BSG: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor. Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM. Interacts with AJAP1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi membrane; focal adhesion; membrane; mitochondrion; integral to plasma membrane; melanosome; plasma membrane; sarcolemma; acrosomal membrane; lipid raft

Molecular Function: mannose binding; protein binding

Biological Process: response to peptide hormone stimulus; extracellular matrix organization and biogenesis; response to cAMP; decidualization; odontogenesis of dentine-containing teeth; response to mercury ion; cellular metabolic process; extracellular matrix disassembly; cell surface receptor linked signal transduction; pyruvate metabolic process; blood coagulation; leukocyte migration; embryo implantation

Disease: Blood Group--ok
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 Research Articles on CD147    1. The expression levels of CD147 and MMP-9 are positively correlated with invasion, metastasis and shorter survival of triple-negative breast cancer patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD147 elisa kitPathways associated with CD147 elisa kit
 Reference Product  PubMed Publications
 SLC16A4 elisa kit  >15 publications with CD147 and SLC16A4
 MMP1 elisa kit  >4 publications with CD147 and MMP1
 SLC16A3 elisa kit  >4 publications with CD147 and SLC16A3
 CAV1 elisa kit  >3 publications with CD147 and CAV1
 SLC16A8 elisa kit  >1 publications with CD147 and SLC16A8
 AJAP1 elisa kit  >1 publications with CD147 and AJAP1
 PPIL2 elisa kit  >1 publications with CD147 and PPIL2
 SLC16A1 elisa kit  >1 publications with CD147 and SLC16A1
 Products by Pathway  Pathway Diagram
 Basigin Interactions Pathway antibodies  Basigin Interactions Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Matrix Metalloproteinases Pathway antibodies  Matrix Metalloproteinases Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Pyruvate Metabolism Pathway antibodies  Pyruvate Metabolism Pathway Diagram
 Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway antibodies  Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Syndecan-1-mediated Signaling Events Pathway antibodies  Syndecan-1-mediated Signaling Events Pathway Diagram
Diseases associated with CD147 elisa kitOrgans/Tissues associated with CD147 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >274 publications with CD147 and Neoplasms
 Carcinoma Antibodies  >131 publications with CD147 and Carcinoma
 Neoplasm Metastasis Antibodies  >73 publications with CD147 and Neoplasm Metastasis
 Neoplasm Invasiveness Antibodies  >54 publications with CD147 and Neoplasm Invasiveness
 Inflammation Antibodies  >43 publications with CD147 and Inflammation
 Immune System Diseases Antibodies  >41 publications with CD147 and Immune System Diseases
 Liver Diseases Antibodies  >37 publications with CD147 and Liver Diseases
 Breast Neoplasms Antibodies  >35 publications with CD147 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >31 publications with CD147 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >30 publications with CD147 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >331 publications with CD147 and Blood
 Brain Antibodies  >169 publications with CD147 and Brain
 Vascular Antibodies  >90 publications with CD147 and Vascular
 Nerve Antibodies  >49 publications with CD147 and Nerve
 Muscle Antibodies  >49 publications with CD147 and Muscle
 Liver Antibodies  >48 publications with CD147 and Liver
 Lung Antibodies  >43 publications with CD147 and Lung
 Eye Antibodies  >39 publications with CD147 and Eye
 Heart Antibodies  >33 publications with CD147 and Heart
 Embryonic Tissue Antibodies  >32 publications with CD147 and Embryonic Tissue
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