EHH60845.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
51,276 Da
NCBI Official Full Name
Complement factor P
UniProt Protein Name
Properdin
UniProt Synonym Protein Names
Complement factor P
UniProt Synonym Gene Names
UniProt Entry Name
PROP_HUMAN
UniProt Comments for CFP
CFP: A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Defects in CFP are the cause of properdin deficiency (PFD). PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: Xp11.4
Cellular Component: extracellular matrix; extracellular space; endoplasmic reticulum lumen; extracellular region
Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; defense response to bacterium; complement activation, alternative pathway; regulation of complement activation; innate immune response; immune response; post-translational protein modification; complement activation
Disease: Properdin Deficiency, X-linked
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Products associated with CFP elisa kit
Diseases associated with CFP elisa kit
Organs/Tissues associated with CFP elisa kit
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