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FDFT1 elisa kit :: Cavy Farnesyl Diphosphate Farnesyl transferase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS014872 FDFT1 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Farnesyl Diphosphate Farnesyl transferase 1 (FDFT1), ELISA Kit

 Also Known As   

Cavy Farnesyl Diphosphate Farnesyl transferase 1 ELISA Kit

 Product Gene Name   

FDFT1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 8; NC_000008.10 (11660190..11696818). Location: 8p23.1-p22
 3D Structure    ModBase 3D Structure for Q6IAX1
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 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FDFT1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FDFT1 purchase    MBS014872 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Farnesyl Diphosphate Farnesyl transferase 1 (FDFT1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FDFT1. The ELISA analytical biochemical technique of the MBS014872 kit is based on FDFT1 antibody-FDFT1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FDFT1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FDFT1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FDFT1. It may not necessarily be applicable to this product.
 NCBI GI #    48146183
 NCBI GeneID    2222
 NCBI Accession #    CAG33314.1 [Other Products]
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 UniProt Primary Accession #    Q6IAX1 [Other Products]
 UniProt Related Accession #    P37268 [Other Products]
 Molecular Weight    48,115 Da
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 NCBI Official Full Name    FDFT1
 NCBI Official Synonym Full Names    farnesyl-diphosphate farnesyltransferase 1
 NCBI Official Symbol    FDFT1 [Similar Products]
 NCBI Official Synonym Symbols   
SS; SQS; DGPT; ERG9
[Similar Products]
 NCBI Protein Information    squalene synthase; squalene synthetase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase
 UniProt Protein Name    FDFT1 protein
 UniProt Gene Name    FDFT1 [Similar Products]
 UniProt Entry Name    Q6IAX1_HUMAN
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 NCBI Summary for FDFT1    This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for FDFT1    FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]

Protein type: Oxidoreductase; Membrane protein, integral; Transferase; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, multi-pass; EC 2.5.1.21

Chromosomal Location of Human Ortholog: 8p23.1-p22

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: farnesyl-diphosphate farnesyltransferase activity; oxidoreductase activity

Biological Process: isoprenoid biosynthetic process; cellular lipid metabolic process; farnesyl diphosphate metabolic process; cholesterol biosynthetic process; steroid biosynthetic process
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 Research Articles on FDFT1    1. FDFT1 and its encoded enzyme, squalene synthase, may play an important role in prostate cancer development and its aggressive phenotypes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FDFT1 elisa kitDiseases associated with FDFT1 elisa kit
 Products by Pathway  Pathway Diagram
 Activation Of Gene Expression By SREBP (SREBF) Pathway antibodies  Activation Of Gene Expression By SREBP (SREBF) Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Cholesterol Biosynthesis Pathway antibodies  Cholesterol Biosynthesis Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPARA Activates Gene Expression Pathway antibodies  PPARA Activates Gene Expression Pathway Diagram
 Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway antibodies  Regulation Of Cholesterol Biosynthesis By SREBP (SREBF) Pathway Diagram
 Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway antibodies  Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with FDFT1 and Neoplasms
 Fatty Liver Antibodies  >3 publications with FDFT1 and Fatty Liver
 Gastrointestinal Diseases Antibodies  >3 publications with FDFT1 and Gastrointestinal Diseases
 Cardiovascular Diseases Antibodies  >3 publications with FDFT1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >2 publications with FDFT1 and Liver Diseases
 Drug Toxicity Antibodies  >2 publications with FDFT1 and Drug Toxicity
 Inflammation Antibodies  >2 publications with FDFT1 and Inflammation
 Fibrosis Antibodies  >2 publications with FDFT1 and Fibrosis
 Nervous System Diseases Antibodies  >2 publications with FDFT1 and Nervous System Diseases
 Liver Neoplasms Antibodies  >1 publications with FDFT1 and Liver Neoplasms
Organs/Tissues associated with FDFT1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >10 publications with FDFT1 and Liver
 Blood Antibodies  >6 publications with FDFT1 and Blood
 Brain Antibodies  >6 publications with FDFT1 and Brain
 Prostate Antibodies  >3 publications with FDFT1 and Prostate
 Heart Antibodies  >3 publications with FDFT1 and Heart
 Stomach Antibodies  >3 publications with FDFT1 and Stomach
 Eye Antibodies  >2 publications with FDFT1 and Eye
 Muscle Antibodies  >1 publications with FDFT1 and Muscle
 Ovary Antibodies  >1 publications with FDFT1 and Ovary
 Pancreas Antibodies  >1 publications with FDFT1 and Pancreas
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