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FOXD3 elisa kit :: Cavy Forkhead Box Protein D3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS010492 FOXD3 elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Forkhead Box Protein D3 (FOXD3), ELISA Kit

 Also Known As   

Cavy Forkhead Box Protein D3 ELISA Kit

 Product Gene Name   

FOXD3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 1; NC_000001.10 (63788730..63790797). Location: 1p31.3
 OMIM    607836
 3D Structure    ModBase 3D Structure for Q9UJU5
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 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FOXD3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FOXD3 purchase    MBS010492 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Forkhead Box Protein D3 (FOXD3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FOXD3. The ELISA analytical biochemical technique of the MBS010492 kit is based on FOXD3 antibody-FOXD3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FOXD3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FOXD3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FOXD3. It may not necessarily be applicable to this product.
 NCBI GI #    6912372
 NCBI GeneID    27022
 NCBI Accession #    NP_036315.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_012183.2 [Other Products]
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 UniProt Primary Accession #    Q9UJU5 [Other Products]
 UniProt Secondary Accession #    Q9BYM2; Q9UDD1 [Other Products]
 UniProt Related Accession #    Q9UJU5 [Other Products]
 Molecular Weight    47,630 Da
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 NCBI Official Full Name    forkhead box protein D3
 NCBI Official Synonym Full Names    forkhead box D3
 NCBI Official Symbol    FOXD3 [Similar Products]
 NCBI Official Synonym Symbols   
AIS1; HFH2; VAMAS2; Genesis
[Similar Products]
 NCBI Protein Information    forkhead box protein D3; HNF3/FH transcription factor genesis
 UniProt Protein Name    Forkhead box protein D3
 UniProt Synonym Protein Names   
HNF3/FH transcription factor genesis
 Protein Family    Forkhead box protein
 UniProt Gene Name    FOXD3 [Similar Products]
 UniProt Synonym Gene Names    HFH2 [Similar Products]
 UniProt Entry Name    FOXD3_HUMAN
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 NCBI Summary for FOXD3    This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1. [provided by RefSeq, Nov 2008]
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 UniProt Comments for FOXD3    FOXD3: Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: nucleoplasm; nuclear chromatin

Molecular Function: protein binding; double-stranded DNA binding; transcription factor activity

Biological Process: embryonic placenta development; transcription, DNA-dependent; somatic stem cell maintenance; in utero embryonic development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; trophectodermal cell differentiation

Disease: Autoimmune Disease, Susceptibility To, 1
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 Research Articles on FOXD3    1. upregulation of ERBB3 is involved in melanoma adapting to RAF/MEK inhibitors through FOXD3
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FOXD3 elisa kitPathways associated with FOXD3 elisa kit
 Reference Product  PubMed Publications
 NANOG elisa kit  >30 publications with FOXD3 and NANOG
 SOX10 elisa kit  >23 publications with FOXD3 and SOX10
 OCT4 elisa kit  >21 publications with FOXD3 and OCT4
 SOX9 elisa kit  >18 publications with FOXD3 and SOX9
 PAX3 elisa kit  >18 publications with FOXD3 and PAX3
 MYF5 elisa kit  >2 publications with FOXD3 and MYF5
 FOXC2 elisa kit  >1 publications with FOXD3 and FOXC2
 NLRP1 elisa kit  >1 publications with FOXD3 and NLRP1
 Products by Pathway  Pathway Diagram
 Neural Crest Differentiation Pathway antibodies  Neural Crest Differentiation Pathway Diagram
 Wnt Signaling Pathway And Pluripotency antibodies  Wnt Signaling Pathway And Pluripotency Diagram
Diseases associated with FOXD3 elisa kitOrgans/Tissues associated with FOXD3 elisa kit
 Disease Name  Pubmed Publications
 Drug Toxicity Antibodies  >2 publications with FOXD3 and Drug Toxicity
 Abnormalities, Multiple Antibodies  >2 publications with FOXD3 and Abnormalities, Multiple
 Sarcoma Antibodies  >2 publications with FOXD3 and Sarcoma
 Ovarian Neoplasms Antibodies  >1 publications with FOXD3 and Ovarian Neoplasms
 Heart Defects, Congenital Antibodies  >1 publications with FOXD3 and Heart Defects, Congenital
 Necrosis Antibodies  >1 publications with FOXD3 and Necrosis
 Respiratory Tract Diseases Antibodies  >1 publications with FOXD3 and Respiratory Tract Diseases
 Abnormalities, Drug-Induced Antibodies  >1 publications with FOXD3 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >41 publications with FOXD3 and Embryonic Tissue
 Eye Antibodies  >7 publications with FOXD3 and Eye
 Intestine Antibodies  >3 publications with FOXD3 and Intestine
 Heart Antibodies  >3 publications with FOXD3 and Heart
 Ear Antibodies  >2 publications with FOXD3 and Ear
 Kidney Antibodies  >2 publications with FOXD3 and Kidney
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