Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow MRP rightarrow Cavy MRP  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Retinoic Acid Receptor beta (RARB) Antibody
 • Period Circadian Protein 2 (Phospho-Ser662) (PER2) Antibody
 • OR5W2 Antibody
 • Glucocorticoid Receptor-beta (GR-beta) ELISA Kit
 • 12-Lipoxygenase (LOX-12) ELISA Kit
 • Glypican 2 (GPC2) ELISA Kit
 • Double Stranded DNA Antibody (DSDNAAB) ELISA Kit
 • Rap Guanine Nucleotide Exchange Factor 1 (RAPGEF1) ELISA Kit
 • Carboxylated Osteocalcin (COC) ELISA Kit
 • Signal Transducer and Activator of Transcription 5B (STAT5B) ELISA Kit
 • Interleukin 9 (IL-9) ELISA Kit
 • 5-Phosphoribosyl 1-Pyrophosphate (PRPP) ELISA Kit
 • Perforin (PRF) ELISA Kit
 • Fatty Acid Binding Protein 5, Epidermal (FABP5) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

MRP elisa kit :: Cavy Myeloid-Related Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS025141 MRP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Myeloid-Related Protein (MRP), ELISA Kit

 Also Known As   

Cavy Myeloid-Related Protein ELISA Kit

 Product Gene Name   

MRP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Current Manual Insert    Request Current Manual
 OMIM    600289
 3D Structure    ModBase 3D Structure for Q16539
Section Bar
 Species Reactivity    Cavy
Section Bar
Section Bar
 Assay Type    Sandwich
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MRP purchase    MBS025141 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myeloid-Related Protein (MRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MRP. The ELISA analytical biochemical technique of the MBS025141 kit is based on MRP antibody-MRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for MRP. It may not necessarily be applicable to this product.
 NCBI GI #    2499600
 NCBI GeneID    1432
 NCBI Accession #    Q16539.3 [Other Products]
Section Bar
 UniProt Primary Accession #    Q16539 [Other Products]
 UniProt Secondary Accession #    O60776; Q13083; Q14084; Q8TDX0; A6ZJ92; A8K6P4; B0LPH0 [Other Products]
 UniProt Related Accession #    Q16539 [Other Products]
 Molecular Weight    41,293 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Mitogen-activated protein kinase 14
 NCBI Official Synonym Full Names    mitogen-activated protein kinase 14
 NCBI Official Symbol    MAPK14 [Similar Products]
 NCBI Official Synonym Symbols   
RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA
[Similar Products]
 NCBI Protein Information    mitogen-activated protein kinase 14; MAP kinase 14; p38alpha Exip; p38 MAP kinase; MAP kinase Mxi2; MAP kinase p38 alpha; CSAID-binding protein; Csaids binding protein; MAX-interacting protein 2; stress-activated protein kinase 2A; p38 mitogen activated protein kinase; mitogen-activated protein kinase p38 alpha; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug-binding protein
 UniProt Protein Name    Mitogen-activated protein kinase 14
 UniProt Synonym Protein Names   
Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a
 Protein Family    MIP-related peptides
 UniProt Gene Name    MAPK14 [Similar Products]
 UniProt Synonym Gene Names    CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; MAP kinase 14; MAPK 14; CSAID-binding protein; CSBP; MAP kinase p38 alpha; SAPK2a [Similar Products]
 UniProt Entry Name    MK14_HUMAN
Section Bar
 NCBI Summary for MRP    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for MRP    P38A: a proline-directed ser/thr MAP kinase, and one of four p38 kinases that play important roles in cellular responses to inflammatory cytokines, DNA damage, oxidative stress, and some GPCRs, leading to direct activation of transcription factors and of other downstream kinases including MSK1, MSK2, eEF2K, MK2, and PRAK. MSK1 and -2 play important roles in the rapid induction of immediate-early genes in response to stress or mitogenic stimuli. MK2 and -3 control gene expression mostly at the post-transcriptional level. eEF2K is important for the elongation of mRNA during translation. Ectodomain shedding of transmembrane proteins is regulated by p38 MAPKs as well. In response to inflammatory stimuli, p38 MAPKs phosphorylate the membrane-associated metalloprotease ADAM17, which then cleaves the ectodomain of TGF-alpha family ligands, a process leading to the activation of EGFR signaling and cell proliferation. In the nucleus, many transcription factors are phosphorylated and activated by p38 MAPKs in response to different stimuli. Classical examples include ATF1, ATF2, ATF6, ELK1, PTPRH, CHOPO, p53 and MEF2C and MEF2A. The p38 MAPKs are emerging as important modulators of gene expression by regulating chromatin modifiers and remodelers. The promoters of several genes involved in the inflammatory response, such as IL6, IL8 and IL12B, display a p38 MAPK-dependent enrichment of histone H3 phosphorylation on 'Ser-10' (H3S10ph) in LPS-stimulated myeloid cells. Interacts directly with HDAC3 interacts directly and selectively to repress ATF2 transcriptional activity, and regulate TNF gene expression in LPS-stimulated cells. Phosphorylates the ubiquitin ligase SIAH2, regulating its activity towards EGLN3. May also inhibit the lysosomal degradation pathway of autophagy by interfering with the intracellular trafficking of the transmembrane protein ATG9. Regulates the endocytosis of membrane receptors that depend on RAB5A. Regulates the clathrin-mediated internalization of EGFR induced by inflammatory cytokines and UV irradiation by phosphorylating the EGFR and RAB5A effectors. Required in mid-fetal development for the growth of embryo-derived blood vessels in the labyrinth layer of the placenta. Plays an essential role in developmental and stress-induced erythropoiesis, through regulation of EPO gene expression. Interacts with casein kinase II subunits CSNK2A1 and CSNK2B. Activated by cell stresses such as DNA damage, heat shock, osmotic shock, anisomycin and sodium arsenite, as well as pro-inflammatory stimuli such as LPS and IL-1. Phosphorylated by ZAP70 in an alternative activation pathway in response to TCR signaling in T-cells, a pathway is inhibited by GADD45A. Four alternatively spliced isoforms of the human protein have been observed. Isoform MXI2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform EXIP may play a role in the early onset of apoptosis

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CMGC; EC 2.7.11.24; Kinase, protein; CMGC group; MAPK family; p38 subfamily; MAPK/p38 subfamily

Chromosomal Location of Human Ortholog: 6p21.3-p21.2

Cellular Component: nucleoplasm; spindle pole; mitochondrion; cytoplasm; cytosol; nucleus

Molecular Function: MAP kinase kinase activity; MAP kinase activity; protein serine/threonine kinase activity; protein binding; NFAT protein binding; ATP binding

Biological Process: nerve growth factor receptor signaling pathway; activation of MAPK activity; stress-activated MAPK cascade; osteoclast differentiation; toll-like receptor 3 signaling pathway; toll-like receptor 5 signaling pathway; cell surface receptor linked signal transduction; regulation of transcription factor activity; transmembrane receptor protein serine/threonine kinase signaling pathway; chondrocyte differentiation; toll-like receptor 4 signaling pathway; cartilage condensation; platelet activation; mitochondrion organization and biogenesis; skeletal muscle development; transcription, DNA-dependent; positive regulation of blood vessel endothelial cell migration; glucose metabolic process; toll-like receptor 2 signaling pathway; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; response to muramyl dipeptide; DNA damage checkpoint; striated muscle cell differentiation; fatty acid oxidation; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; myoblast cell differentiation involved in skeletal muscle regeneration; apoptosis; cell morphogenesis; chemotaxis; signal transduction; toll-like receptor 10 signaling pathway; lipopolysaccharide-mediated signaling pathway; angiogenesis; MyD88-independent toll-like receptor signaling pathway; positive regulation of erythrocyte differentiation; organelle organization and biogenesis; DNA damage response, signal transduction; positive regulation of myoblast differentiation; MyD88-dependent toll-like receptor signaling pathway; peptidyl-serine phosphorylation; positive regulation of protein import into nucleus; Ras protein signal transduction; toll-like receptor signaling pathway; positive regulation of muscle cell differentiation; innate immune response; gene expression; blood coagulation; vascular endothelial growth factor receptor signaling pathway; cell motility
Table BarTOPTable Bar
 Research Articles on MRP    1. results demonstrated that p38 and ERK1/2 played crucial positive roles in adipogenesis, and FAK, RhoA/ROCK and cytoskeleton played negative roles
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with MRP elisa kitPathways associated with MRP elisa kit
 Reference Product  PubMed Publications
 MAPKAPK2 elisa kit  >21 publications with MRP and MAPKAPK2
 MAP2K6 elisa kit  >18 publications with MRP and MAP2K6
 MAP2K3 elisa kit  >15 publications with MRP and MAP2K3
 ATF2 elisa kit  >7 publications with MRP and ATF2
 DUSP1 elisa kit  >5 publications with MRP and DUSP1
 MEF2C elisa kit  >2 publications with MRP and MEF2C
 DUSP10 elisa kit  >2 publications with MRP and DUSP10
 DUSP16 elisa kit  >1 publications with MRP and DUSP16
 MEF2A elisa kit  >1 publications with MRP and MEF2A
 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of PPARGC1A (PGC-1alpha) By Phosphorylation Pathway antibodies  Activation Of PPARGC1A (PGC-1alpha) By Phosphorylation Pathway Diagram
 Activation Of The AP-1 Family Of Transcription Factors Pathway antibodies  Activation Of The AP-1 Family Of Transcription Factors Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with MRP elisa kitOrgans/Tissues associated with MRP elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >84 publications with MRP and Neoplasms
 Inflammation Antibodies  >75 publications with MRP and Inflammation
 Necrosis Antibodies  >62 publications with MRP and Necrosis
 Nervous System Diseases Antibodies  >25 publications with MRP and Nervous System Diseases
 Heart Diseases Antibodies  >23 publications with MRP and Heart Diseases
 Cell Transformation, Neoplastic Antibodies  >18 publications with MRP and Cell Transformation, Neoplastic
 Myocardial Ischemia Antibodies  >14 publications with MRP and Myocardial Ischemia
 Fibrosis Antibodies  >12 publications with MRP and Fibrosis
 Lung Neoplasms Antibodies  >12 publications with MRP and Lung Neoplasms
 Adenocarcinoma Antibodies  >11 publications with MRP and Adenocarcinoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >75 publications with MRP and Blood
 Muscle Antibodies  >63 publications with MRP and Muscle
 Heart Antibodies  >42 publications with MRP and Heart
 Lung Antibodies  >30 publications with MRP and Lung
 Bone Antibodies  >26 publications with MRP and Bone
 Liver Antibodies  >26 publications with MRP and Liver
 Brain Antibodies  >23 publications with MRP and Brain
 Vascular Antibodies  >21 publications with MRP and Vascular
 Intestine Antibodies  >14 publications with MRP and Intestine
 Kidney Antibodies  >13 publications with MRP and Kidney
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions