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SLA elisa kit :: Cavy Soluble Liver Antigen ELISA Kit

Scan QR to view Datasheet Catalog #    MBS011539 SLA elisa kit
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Soluble Liver Antigen (SLA), ELISA Kit

 Also Known As   

Cavy Soluble Liver Antigen ELISA Kit

 Product Gene Name   

SLA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 4; NC_000004.11 (25121627..25162204, complement). Location: 4p15.2
 OMIM    613009
 3D Structure    ModBase 3D Structure for Q9HD40
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 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLA purchase    MBS011539 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Soluble Liver Antigen (SLA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLA. The ELISA analytical biochemical technique of the MBS011539 kit is based on SLA antibody-SLA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SLA. It may not necessarily be applicable to this product.
 NCBI GI #    7652498
 NCBI GeneID    51091
 NCBI Accession #    AAD33963.2 [Other Products]
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 UniProt Primary Accession #    Q9HD40 [Other Products]
 UniProt Secondary Accession #    Q0D2P3; Q17RT1; Q9NXZ5; Q9UGM9; Q9Y353; A8K8W1 [Other Products]
 UniProt Related Accession #    Q9HD40 [Other Products]
 Molecular Weight    55,726 Da
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 NCBI Official Full Name    soluble liver antigen/liver pancreas antigen
 NCBI Official Synonym Full Names    Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
 NCBI Official Symbol    SEPSECS [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    O-phosphoseryl-tRNA(Sec) selenium transferase; O-phosphoseryl-tRNA(Sec) selenium transferase; SLA-p35; SLA/LP autoantigen; soluble liver antigen; liver-pancreas antigen; UGA suppressor tRNA-associated protein; tRNA(Ser/Sec)-associated antigenic protein; soluble liver antigen/liver pancreas antigen
 UniProt Protein Name    O-phosphoseryl-tRNA(Sec) selenium transferase
 UniProt Synonym Protein Names   
Liver-pancreas antigen; LP; SLA-p35; SLA/LP autoantigen; Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS; Soluble liver antigen; SLA; UGA suppressor tRNA-associated protein; tRNA(Ser/Sec)-associated antigenic protein
 Protein Family    S-layer protein
 UniProt Gene Name    SEPSECS [Similar Products]
 UniProt Synonym Gene Names    TRNP48; LP; Sec synthase; SepSecS; SLA [Similar Products]
 UniProt Entry Name    SPCS_HUMAN
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 NCBI Summary for SLA    The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).[provided by RefSeq, Mar 2011]
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 UniProt Comments for SLA    SLA/LP: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Defects in SEPSECS are the cause of pontocerebellar hypoplasia type 2D (PCH2D). PCH2D is a disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound mental retardation, spasticity, and variable seizures. Belongs to the SepSecS family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Transferase; RNA-binding

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; transferase activity, transferring selenium-containing groups; pyridoxal phosphate binding; tRNA binding

Biological Process: selenocysteine incorporation

Disease: Pontocerebellar Hypoplasia, Type 2d
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 Research Articles on SLA    1. Three SNPs in SEPSECS and SEPHS1 were found to significantly interact with serum selenium level and Crohn's Disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLA elisa kitPathways associated with SLA elisa kit
 Reference Product  PubMed Publications
 PSTK elisa kit  >6 publications with SLA and PSTK
 SELS elisa kit  >1 publications with SLA and SELS
 SEPHS1 elisa kit  >1 publications with SLA and SEPHS1
 Products by Pathway  Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Aminoacyl-tRNA Biosynthesis Pathway antibodies  Aminoacyl-tRNA Biosynthesis Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
 Selenocompound Metabolism Pathway antibodies  Selenocompound Metabolism Pathway Diagram
 Selenocompound Metabolism Pathway antibodies  Selenocompound Metabolism Pathway Diagram
Diseases associated with SLA elisa kitOrgans/Tissues associated with SLA elisa kit
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >1 publications with SLA and Immune System Diseases
 Liver Diseases Antibodies  >1 publications with SLA and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with SLA and Brain
 Liver Antibodies  >1 publications with SLA and Liver
 Blood Antibodies  >1 publications with SLA and Blood
 Muscle Antibodies  >1 publications with SLA and Muscle
 Embryonic Tissue Antibodies  >1 publications with SLA and Embryonic Tissue
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