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alpha-SNCO elisa kit :: Cavy alpha Synuclein Oligomer ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017219 alpha-SNCO elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

alpha Synuclein Oligomer (alpha-SNCO), ELISA Kit

 Also Known As   

Cavy alpha Synuclein Oligomer ELISA Kit

 Product Gene Name   

alpha-SNCO elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P13395
 Species Reactivity    Cavy
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of alpha-SNCO elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for alpha-SNCO purchase    MBS017219 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the alpha Synuclein Oligomer (alpha-SNCO) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing alpha-SNCO. The ELISA analytical biochemical technique of the MBS017219 kit is based on alpha-SNCO antibody-alpha-SNCO antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect alpha-SNCO antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, alpha-SNCO. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for alpha-SNCO. It may not necessarily be applicable to this product.
 NCBI GI #    442629562
 NCBI GeneID    38231
 NCBI Accession #    NP_001261288.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001274359.1 [Other Products]
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 UniProt Primary Accession #    P13395 [Other Products]
 UniProt Secondary Accession #    Q26340; Q3KN50; Q8SZW7; Q9W085 [Other Products]
 UniProt Related Accession #    P13395 [Other Products]
 Molecular Weight    278,303 Da
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 NCBI Official Full Name    alpha spectrin, isoform D
 NCBI Official Synonym Full Names    alpha Spectrin
 NCBI Official Symbol    alpha-Spec [Similar Products]
 NCBI Official Synonym Symbols   
3A9; alfa-Spec; alpha; alpha-Sp; alpha-Spc; alpha-Spe; alpha-spec; alpha-SPEC; alpha-Spect; alpha-spectrin; alpha-Spectrin; alphaSp; alphaSpec; alphaSpectrin; anon-EST:fe2E2; CG1977; DmelCG1977; dre3; FBtr0072789; FCP-B; klo; l(3)04276; l(3)62Bd; l(3)alph
[Similar Products]
 NCBI Protein Information    CG1977 gene product from transcript CG1977-RA; CG1977-PA; CG1977-PB; CG1977-PC; CG1977-PD; aSpc 3A9; alpha spectrin; alpha-SPECTRIN; alpha-Spec-PA; alpha-Spec-PB; alpha-Spec-PC; alpha-Spec-PD; alpha-spectrin II; alphaSpectrin; anon-fast-evolving-2E2; klotzchen
 UniProt Protein Name    Spectrin alpha chain
 UniProt Gene Name    alpha-Spec [Similar Products]
 UniProt Synonym Gene Names    SPEC-A [Similar Products]
 UniProt Entry Name    SPTCA_DROME
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 UniProt Comments for alpha-SNCO    Function: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Essential for larval survival and development. Stabilizes cell to cell interactions that are critical for the maintenance of cell shape and subcellular organization within embryonic tissues. Lva and spectrin may form a Golgi-based scaffold that mediates interaction of Golgi bodies with microtubules and facilitates Golgi-derived membrane secretion required for the formation of furrows during cellularization. Ref.5 Ref.7 Ref.8

Subunit structure: Native spectrin molecule is a tetramer composed of two antiparallel heterodimers joined head to head so that each end of the native molecule includes the C-terminus of the alpha subunit and the N-terminus of the beta subunit. Interacts with calmodulin in a calcium-dependent manner, interacts with F-actin and also interacts with Lva. Interacts with Ten-m. Ref.8 Ref.13

Subcellular location: Cytoplasm › cytoskeleton. Golgi apparatus. Note: Near the inner surface of the plasma membrane of nearly all cells. Lva-alpha-spectrin complexes are found at the Golgi. Ref.8

Tissue specificity: A substantial pool of maternal protein in the egg undergoes dynamic changes in distribution early in embryogenesis. In gastrulated embryo, the highest level of protein is found in the respiratory tract cells and the lowest in parts of the forming gut. Ref.9

Developmental stage: Expressed both maternally and zygotically.

Miscellaneous: Its transcript shares the first untranslated exon with the dlt transcript, suggesting a common regulation.

Sequence similarities: Belongs to the spectrin family.Contains 2 EF-hand domains.Contains 1 SH3 domain.Contains 22 spectrin repeats.

Sequence caution: The sequence AAL39886.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence ABA81823.1 differs from that shown. Reason: Frameshift at position 1549.
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 Research Articles on alpha-SNCO    1. Model in which alphabeta-spectrin directly couples lipid uptake at the plasma membrane to lipid droplet growth in the cytoplasm. In contrast, strong overexpression of beta-spectrin caused fat body atrophy and larval lethality.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with alpha-SNCO elisa kitDiseases associated with alpha-SNCO elisa kit
 Products by Pathway  Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Interaction Between L1 And Ankyrins Pathway antibodies  Interaction Between L1 And Ankyrins Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 NCAM Signaling For Neurite Out-growth Pathway antibodies  NCAM Signaling For Neurite Out-growth Pathway Diagram
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >28 publications with alpha-SNCO and Brain Diseases
 Disease Models, Animal Antibodies  >13 publications with alpha-SNCO and Disease Models, Animal
 Epilepsy Antibodies  >3 publications with alpha-SNCO and Epilepsy
 Somatosensory Disorders Antibodies  >2 publications with alpha-SNCO and Somatosensory Disorders
 Diabetic Neuropathies Antibodies  >1 publications with alpha-SNCO and Diabetic Neuropathies
 Tuberous Sclerosis Antibodies  >1 publications with alpha-SNCO and Tuberous Sclerosis
 Cognition Disorders Antibodies  >1 publications with alpha-SNCO and Cognition Disorders
 Dyskinesias Antibodies  >1 publications with alpha-SNCO and Dyskinesias
 Seizures Antibodies  >1 publications with alpha-SNCO and Seizures
Organs/Tissues associated with alpha-SNCO elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >138 publications with alpha-SNCO and Blood
 Head Antibodies  >16 publications with alpha-SNCO and Head
 Ovary Antibodies  >7 publications with alpha-SNCO and Ovary
 Gonad Antibodies  >6 publications with alpha-SNCO and Gonad
 Embryonic Tissue Antibodies  >5 publications with alpha-SNCO and Embryonic Tissue
 Testis Antibodies  >1 publications with alpha-SNCO and Testis
 Uncharacterized Tissue Antibodies  >1 publications with alpha-SNCO and Uncharacterized Tissue
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