NP_116674.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
1-phosphatidylinositol-3-phosphate 5-kinase
NCBI Official Synonym Symbols
NCBI Protein Information
1-phosphatidylinositol-3-phosphate 5-kinase
UniProt Protein Name
1-phosphatidylinositol 3-phosphate 5-kinase FAB1
UniProt Synonym Protein Names
Type III PIP kinase; PIPkin-III
UniProt Synonym Gene Names
YFR019W; Phosphatidylinositol 3-phosphate 5-kinase; PIPkin-III [Similar Products]
UniProt Entry Name
FAB1_YEAST
UniProt Comments for FAB1
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. The product of the reaction it catalyzes functions as an important regulator of vacuole homeostasis perhaps by controlling membrane flux to and/or from the vacuole. Hyperosmotic shock-induced increase in the levels of PtdIns(3,5)P2 requires the presence of VAC7, VAC14, and/or FIG4.
Research Articles on FAB1
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Products associated with FAB1 elisa kit
Pathways associated with FAB1 elisa kit
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