AAA35482.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
9,448 Da
NCBI Official Full Name
12-lipoxygenase, partial
NCBI Official Synonym Full Names
arachidonate 15-lipoxygenase
NCBI Protein Information
arachidonate 15-lipoxygenase; 15-LOX; 15-lipooxygenase-1; arachidonate omega-6 lipoxygenase
UniProt Protein Name
12-lipoxygenase
UniProt Entry Name
Q12938_HUMAN
UniProt Comments for LOX-12
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family.
Protein type: EC 1.13.11.31; Oxidoreductase; EC 1.13.11.33; Motility/polarity/chemotaxis; Lipid Metabolism - arachidonic acid; Lipid Metabolism - linoleic acid
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol
Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; hepoxilin A3 synthase activity; arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding
Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; wound healing; phosphatidylethanolamine biosynthetic process; leukotriene metabolic process; bone mineralization; lipoxygenase pathway; positive regulation of actin filament polymerization; negative regulation of adaptive immune response; arachidonic acid metabolic process; hepoxilin biosynthetic process; inflammatory response; apoptotic cell clearance
Research Articles on LOX-12
Precautions
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Pathways associated with LOX-12 elisa kit
Diseases associated with LOX-12 elisa kit
Organs/Tissues associated with LOX-12 elisa kit
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