NP_001143.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,852 Da
NCBI Official Full Name
ADP/ATP translocase 2
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
NCBI Protein Information
ADP/ATP translocase 2; ANT 2; ADP/ATP carrier protein; ADP,ATP carrier protein 2; solute carrier family 25 member 5; ADP,ATP carrier protein, fibroblast isoform; adenine nucleotide translocator 2 (fibroblast)
UniProt Protein Name
ADP/ATP translocase 2
UniProt Synonym Protein Names
ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; Adenine nucleotide translocator 2; ANT 2; Solute carrier family 25 member 5Cleaved into the following chain:ADP/ATP translocase 2, N-terminally processed
UniProt Synonym Gene Names
UniProt Entry Name
ADT2_HUMAN
NCBI Summary for SLC25A5
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
UniProt Comments for SLC25A5
SLC25A5: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the mitochondrial carrier family.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Mitochondrial; Membrane protein, integral
Chromosomal Location of Human Ortholog: Xq24
Cellular Component: membrane; mitochondrion; integral to plasma membrane; mitochondrial inner membrane; nucleus
Molecular Function: protein binding; adenine transmembrane transporter activity
Biological Process: adenine transport; viral reproduction; transport; positive regulation of cell proliferation; energy reserve metabolic process; regulation of insulin secretion; transmembrane transport; chromosome segregation
Research Articles on SLC25A5
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Products associated with SLC25A5 elisa kit
Pathways associated with SLC25A5 elisa kit
Diseases associated with SLC25A5 elisa kit
Organs/Tissues associated with SLC25A5 elisa kit
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