Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow ALPL rightarrow Chicken ALPL  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • proprotein convertase subtilisin-kexin type 9 (PCSK9) ELISA Kit
 • CX3CL1-Fractalkine Recombinant Protein
 • CD282 (TLR2) Antibody
 • B4GALT1 Antibody
 • resolvin D1 (RvD1) ELISA Kit
 • complement component 9 (C9) ELISA Kit
 • Billverdin Reductase Antibody
 • Human IgM protein (HRP) Immunoglobulin
 • Unconventional myosin-VIIa (MYO7A), partial Recombinant Protein
 • Azurin (BPP3406) Recombinant Protein
 • CD200  Antibody
 • Interleukin-4 (rIL 4) Recombinant Protein
 • Nav1.7 (SCN9A) Antibody
 • chromosome 14 open reading frame 100 (C14orf100) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

ALPL elisa kit :: Chicken Alkaline Phosphatase, Liver/Bone/Kidney ELISA Kit

Scan QR to view Datasheet Catalog #    MBS743165 ALPL elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Alkaline Phosphatase, Liver/Bone/Kidney (ALPL), ELISA Kit

 Also Known As   

Chicken Alkaline Phosphatase, Liver/Bone/Kidney ELISA Kit

 Product Gene Name   

ALPL elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Manual Insert    Request Manual
 OMIM    241510
Section Bar
 Species Reactivity    Chicken
Section Bar
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ALPL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ALPL purchase    MBS743165 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Alkaline Phosphatase, Liver/Bone/Kidney (ALPL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ALPL. The ELISA analytical biochemical technique of the MBS743165 kit is based on ALPL antibody-ALPL antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ALPL antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ALPL. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 Product Categories/Family for ALPL elisa kit    Cancer
NCBI/Uniprot data below describe general gene information for ALPL. It may not necessarily be applicable to this product.
 NCBI GI #    187954299
 NCBI GeneID    249
 NCBI Accession #    AAI36326.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    O75090; Q2TAI7; Q59EJ7; Q5BKZ5; Q5VTG5; Q6NZI8; Q8WU32; A1A4E7; B2RMP8; B7Z387; B7Z4Y6 [Other Products]
 UniProt Related Accession #    P05186 [Other Products]
 Molecular Weight    51,045 Da
Table BarTOPTable Bar
 NCBI Official Full Name    Alkaline phosphatase, liver/bone/kidney
 NCBI Official Synonym Full Names    alkaline phosphatase, liver/bone/kidney
 NCBI Official Symbol    ALPL [Similar Products]
 NCBI Official Synonym Symbols   
HOPS; TNAP; APTNAP; TNSALP; AP-TNAP
[Similar Products]
 NCBI Protein Information    alkaline phosphatase, tissue-nonspecific isozyme; glycerophosphatase; tissue-nonspecific ALP; alkaline phosphomonoesterase; liver/bone/kidney-type alkaline phosphatase; alkaline phosphatase liver/bone/kidney isozyme
 UniProt Protein Name    Alkaline phosphatase, tissue-nonspecific isozyme
 UniProt Synonym Protein Names   
Alkaline phosphatase liver/bone/kidney isozyme
 Protein Family    Alkaline phosphatase
 UniProt Gene Name    ALPL [Similar Products]
 UniProt Synonym Gene Names    AP-TNAP; TNSALP [Similar Products]
 UniProt Entry Name    PPBT_HUMAN
Section Bar
 NCBI Summary for ALPL    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Section Bar
 UniProt Comments for ALPL    ALPL: This isozyme may play a role in skeletal mineralization. Defects in ALPL are a cause of hypophosphatasia (HOPS). HOPS is an inherited metabolic bone disease characterized by defective skeletal mineralization. Four hypophosphatasia forms are distinguished, depending on the age of onset: perinatal, infantile, childhood and adult type. The perinatal form is the most severe and is almost always fatal. Patients with only premature loss of deciduous teeth, but with no bone disease are regarded as having odontohypophosphatasia (odonto). Defects in ALPL are a cause of hypophosphatasia childhood type (HOPSC). Defects in ALPL are a cause of hypophosphatasia infantile type (HOPSI). Belongs to the alkaline phosphatase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Cofactor and Vitamin Metabolism - folate biosynthesis; Phosphatase (non-protein); EC 3.1.3.1; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1p36.12

Cellular Component: extracellular matrix; extracellular space; membrane; plasma membrane; integral to membrane

Molecular Function: pyrophosphatase activity; protein binding; alkaline phosphatase activity; metal ion binding

Biological Process: osteoblast differentiation; response to antibiotic; response to vitamin D; dephosphorylation; response to glucocorticoid stimulus; reproductive developmental process; response to lipopolysaccharide; skeletal development; endochondral ossification

Disease: Hypophosphatasia, Infantile; Hypophosphatasia, Adult; Hypophosphatasia, Childhood
Table BarTOPTable Bar
 Research Articles on ALPL    1. ABO locus is a major determinant for serum ALP levels in Chinese Han population.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Pathways associated with ALPL elisa kitDiseases associated with ALPL elisa kit
 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Folate Biosynthesis Pathway antibodies  Folate Biosynthesis Pathway Diagram
 Folate Biosynthesis Pathway antibodies  Folate Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 TNF-alpha/NF-kB Signaling Pathway antibodies  TNF-alpha/NF-kB Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >12 publications with ALPL and Kidney Diseases
 Seizures Antibodies  >10 publications with ALPL and Seizures
 Cardiovascular Diseases Antibodies  >9 publications with ALPL and Cardiovascular Diseases
 Inflammation Antibodies  >8 publications with ALPL and Inflammation
 Pain Antibodies  >7 publications with ALPL and Pain
 Calcinosis Antibodies  >5 publications with ALPL and Calcinosis
 Liver Diseases Antibodies  >5 publications with ALPL and Liver Diseases
 Necrosis Antibodies  >4 publications with ALPL and Necrosis
 Hypertension Antibodies  >4 publications with ALPL and Hypertension
 Hypertrophy Antibodies  >4 publications with ALPL and Hypertrophy
Organs/Tissues associated with ALPL elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >166 publications with ALPL and Bone
 Blood Antibodies  >52 publications with ALPL and Blood
 Kidney Antibodies  >41 publications with ALPL and Kidney
 Liver Antibodies  >39 publications with ALPL and Liver
 Connective Tissue Antibodies  >35 publications with ALPL and Connective Tissue
 Mouth Antibodies  >14 publications with ALPL and Mouth
 Adipose Tissue Antibodies  >14 publications with ALPL and Adipose Tissue
 Brain Antibodies  >14 publications with ALPL and Brain
 Skin Antibodies  >7 publications with ALPL and Skin
 Embryonic Tissue Antibodies  >7 publications with ALPL and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions