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AATK elisa kit :: Chicken Apoptosis Associated Tyrosine Kinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS024699 AATK elisa kit
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 Product Name   

Apoptosis Associated Tyrosine Kinase (AATK), ELISA Kit

 Also Known As   

Chicken Apoptosis Associated Tyrosine Kinase ELISA Kit

 Product Gene Name   

AATK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 17; NC_000017.10 (79091095..79139872, complement). Location: 17q25.3
 OMIM    605276
 3D Structure    ModBase 3D Structure for Q6ZMQ8
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 Species Reactivity    Chicken
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AATK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AATK purchase    MBS024699 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Apoptosis Associated Tyrosine Kinase (AATK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AATK. The ELISA analytical biochemical technique of the MBS024699 kit is based on AATK antibody-AATK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AATK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AATK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AATK. It may not necessarily be applicable to this product.
 NCBI GI #    28703754
 NCBI GeneID    9625
 NCBI Accession #    AAH47378.1 [Other Products]
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 UniProt Primary Accession #    Q6ZMQ8 [Other Products]
 UniProt Secondary Accession #    O75136; Q6ZN31; Q86X28 [Other Products]
 UniProt Related Accession #    Q6ZMQ8 [Other Products]
 Molecular Weight    144,569 Da
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 NCBI Official Full Name    AATK protein, partial
 NCBI Official Synonym Full Names    apoptosis-associated tyrosine kinase
 NCBI Official Symbol    AATK [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase LMTK1; p35-binding protein; CDK5-binding protein; lemur tyrosine kinase 1; brain apoptosis-associated tyrosine kinase
 UniProt Protein Name    Serine/threonine-protein kinase LMTK1
 UniProt Synonym Protein Names   
Apoptosis-associated tyrosine kinase; AATYK; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    AATK [Similar Products]
 UniProt Synonym Gene Names    AATYK; KIAA0641; LMR1; LMTK1; AATYK; p35BP [Similar Products]
 UniProt Entry Name    LMTK1_HUMAN
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 NCBI Summary for AATK    The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for AATK    Lmr1: a protein kinase kinase of the Lmr family. Predominantly expressed in the nervous system and is involved in neurite extension and apoptosis of cerebellar granule cells. Contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. May be necessary for the induction of growth arrest and/or apoptosis of myeloid cells induced by cytokine withdrawal, such as IL3, and during G-CSF-induced terminal differentiation of myeloblasts to granulocytes. Four alternatively spliced isoforms have been reported.

Protein type: Protein kinase, tyrosine (receptor); Membrane protein, integral; Protein kinase, TK; Kinase, protein; EC; TK group; Lmr family

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: recycling endosome; endoplasmic reticulum; perinuclear region of cytoplasm; integral to membrane

Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; ATP binding

Biological Process: neuron apoptosis; negative regulation of axon extension; brain development; Rab protein signal transduction
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 Research Articles on AATK    1. This paper deals with the mouse ortholog.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AATK elisa kitDiseases associated with AATK elisa kit
 Reference Product  PubMed Publications
 CDK5 elisa kit  >3 publications with AATK and CDK5
 STK39 elisa kit  >1 publications with AATK and STK39
 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >1 publications with AATK and Insulin Resistance
 Hyperplasia Antibodies  >1 publications with AATK and Hyperplasia
 Inflammation Antibodies  >1 publications with AATK and Inflammation
Organs/Tissues associated with AATK elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with AATK and Brain
 Nerve Antibodies  >6 publications with AATK and Nerve
 Intestine Antibodies  >1 publications with AATK and Intestine
 Pancreas Antibodies  >1 publications with AATK and Pancreas
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