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AhR elisa kit :: Chicken Aryl Hydrocarbon Receptor (AhR) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS262394
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $475 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Aryl Hydrocarbon Receptor (AhR), ELISA Kit

★Popular Item★
 Also Known As   

Chicken Aryl Hydrocarbon Receptor (AhR) ELISA Kit

 Product Gene Name   

AhR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    600253
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 Species Reactivity    Chicken
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 Samples    Chicken serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant AhR concentration
 Assay Type    Sandwich
 Detection Range    20 ng/ml-0.312 ng/ml
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AhR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AhR purchase    MBS262394 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Aryl Hydrocarbon Receptor (AhR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 20 ng/ml-0.312 ng/ml in biological research samples containing AhR. The ELISA analytical biochemical technique of the MBS262394 kit is based on AhR antibody-AhR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AhR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AhR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Chicken serum, plasma or Cell Culture Supernatant and organizations in the natural and recombinant AhR concentration. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for AhR elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Chicken AhR monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Testing Data/Standard Curve (for reference only) of AhR elisa kit    AhR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS262394. Click to request current manual
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NCBI/Uniprot data below describe general gene information for AhR. It may not necessarily be applicable to this product.
 NCBI GI #    4502003
 NCBI GeneID    196
 NCBI Accession #    NP_001612.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001621.4 [Other Products]
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 UniProt Secondary Accession #    Q13728; Q13803; Q13804; A4D130 [Other Products]
 UniProt Related Accession #    P35869 [Other Products]
 Molecular Weight    96,147 Da
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 NCBI Official Full Name    aryl hydrocarbon receptor
 NCBI Official Synonym Full Names    aryl hydrocarbon receptor
 NCBI Official Symbol    AHR [Similar Products]
 NCBI Official Synonym Symbols   
bHLHe76
[Similar Products]
 NCBI Protein Information    aryl hydrocarbon receptor; AH-receptor; ah receptor; aromatic hydrocarbon receptor; class E basic helix-loop-helix protein 76
 UniProt Protein Name    Aryl hydrocarbon receptor
 UniProt Synonym Protein Names   
Class E basic helix-loop-helix protein 76; bHLHe76
 Protein Family    Aldehyde reductase
 UniProt Gene Name    AHR [Similar Products]
 UniProt Synonym Gene Names    BHLHE76; Ah receptor; AhR; bHLHe76 [Similar Products]
 UniProt Entry Name    AHR_HUMAN
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 NCBI Summary for AhR    This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AhR    AHR: a nuclear receptor for aryl hydrocarbons involved in xenobiotic metabolism, cell cycle regulation, and development in response to both endogenous and environmental signals. AhR was initially identified as a receptor for dioxins, which are environmental pollutants generated by waste incineration and other industrial processes . AhR ligands include polycyclic aromatic hydrocarbons, including the carcinogen benzo(a)pyrene and other components of cigarette smoke. Naturally occurring AhR ligands include flavonoids, which are aromatic plant secondary compounds commonly found in vegetables and fruits. Cytoplasmic aryl hydrocarbon receptors are found in protein complexes with heat shock proteins. Upon ligand binding, AhR dissociates from heat shock proteins and translocate to the nucleus where it dimerizes with AhR nuclear translocator (ARNT, HIF-1b). The AhR/ARNT heterodimer binds to nuclear xenobiotic response elements to control the expression of genes associated with xenobiotic metabolism, including several cytochrome P450 genes. AhR is ubiquitously expressed and is thought to play a role in regulation of cell proliferation and differentiation, cytokine expression, and xenobiotic metabolism. Research studies link AhR activity with the control of regulatory T-cell and T-helper 17 cell differentiation, regulation of the inflammatory response, and the onset of lung cancer.

Protein type: Nuclear receptor; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7p15

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus

Molecular Function: protein dimerization activity; RNA polymerase II transcription factor activity, enhancer binding; ligand-dependent nuclear receptor activity; signal transducer activity; protein binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; Hsp90 protein binding; transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; prostate gland development; blood vessel development; intracellular receptor-mediated signaling pathway; apoptosis; positive regulation of transcription, DNA-dependent; response to toxin; negative regulation of transcription from RNA polymerase II promoter; cell cycle; regulation of transcription from RNA polymerase II promoter; response to xenobiotic stimulus; regulation of transcription, DNA-dependent; regulation of gene expression; xenobiotic metabolic process; positive regulation of transcription from RNA polymerase II promoter; regulation of B cell proliferation; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent; positive regulation of transcriptional preinitiation complex assembly
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 Research Articles on AhR    1. Taken together, cell type specific in vivo evidence for AhR functions indicates that osteoclastic AhR plays a significant role in maintenance of bone homeostasis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AhR elisa kitPathways associated with AhR elisa kit
 Reference Product  PubMed Publications
 CYP1A1 elisa kit  >1252 publications with AhR and CYP1A1
 ARNT elisa kit  >597 publications with AhR and ARNT
 CYP1B1 elisa kit  >337 publications with AhR and CYP1B1
 SRC elisa kit  >41 publications with AhR and SRC
 AIP elisa kit  >22 publications with AhR and AIP
 RELA elisa kit  >15 publications with AhR and RELA
 ESR1 elisa kit  >10 publications with AhR and ESR1
 RB1 elisa kit  >5 publications with AhR and RB1
 HSP90AA1 elisa kit  >3 publications with AhR and HSP90AA1
 SMARCA4 elisa kit  >2 publications with AhR and SMARCA4
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram
Diseases associated with AhR elisa kitOrgans/Tissues associated with AhR elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1112 publications with AhR and Inflammation
 Neoplasms Antibodies  >792 publications with AhR and Neoplasms
 Liver Diseases Antibodies  >296 publications with AhR and Liver Diseases
 Liver Neoplasms Antibodies  >234 publications with AhR and Liver Neoplasms
 Breast Neoplasms Antibodies  >228 publications with AhR and Breast Neoplasms
 Necrosis Antibodies  >166 publications with AhR and Necrosis
 Carcinoma, Hepatocellular Antibodies  >141 publications with AhR and Carcinoma, Hepatocellular
 Neoplasms, Experimental Antibodies  >135 publications with AhR and Neoplasms, Experimental
 Hyperplasia Antibodies  >133 publications with AhR and Hyperplasia
 Pneumonia Antibodies  >123 publications with AhR and Pneumonia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1370 publications with AhR and Blood
 Lung Antibodies  >1228 publications with AhR and Lung
 Liver Antibodies  >968 publications with AhR and Liver
 Muscle Antibodies  >338 publications with AhR and Muscle
 Kidney Antibodies  >319 publications with AhR and Kidney
 Heart Antibodies  >312 publications with AhR and Heart
 Skin Antibodies  >240 publications with AhR and Skin
 Vascular Antibodies  >231 publications with AhR and Vascular
 Brain Antibodies  >217 publications with AhR and Brain
 Bone Antibodies  >177 publications with AhR and Bone
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