NP_004923.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
73,864 Da
NCBI Official Full Name
cadherin-6 preproprotein
NCBI Official Synonym Full Names
cadherin 6, type 2, K-cadherin (fetal kidney)
NCBI Official Synonym Symbols
NCBI Protein Information
cadherin-6
UniProt Protein Name
Cadherin-6
UniProt Synonym Protein Names
Kidney cadherin; K-cadherin
UniProt Synonym Gene Names
UniProt Entry Name
CADH6_HUMAN
NCBI Summary for CDH6
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011]
UniProt Comments for CDH6
CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Cell adhesion
Chromosomal Location of Human Ortholog: 5p13.3
Cellular Component: plasma membrane; integral to membrane
Molecular Function: calcium ion binding
Biological Process: intercellular junction assembly and maintenance; homophilic cell adhesion; cell adhesion
Research Articles on CDH6
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Products associated with CDH6 elisa kit
Pathways associated with CDH6 elisa kit
Diseases associated with CDH6 elisa kit
Organs/Tissues associated with CDH6 elisa kit
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