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CNTF elisa kit :: Chicken Ciliary Neurotrophic Factor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS028756 CNTF elisa kit
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ciliary Neurotrophic Factor (CNTF), ELISA Kit

 Also Known As   

Chicken Ciliary Neurotrophic Factor ELISA Kit

 Product Gene Name   

CNTF elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.9 (58390146..58393206). Location: 11q12.2
 OMIM    118945
 3D Structure    ModBase 3D Structure for P26441
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 Species Reactivity    Chicken
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CNTF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CNTF purchase    MBS028756 is a ready-to-use microwell, strip-or-full plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ciliary Neurotrophic Factor (CNTF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CNTF. The ELISA analytical biochemical technique of the MBS028756 kit is based on CNTF antibody-CNTF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CNTF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CNTF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CNTF. It may not necessarily be applicable to this product.
 NCBI GI #    4758020
 NCBI GeneID    1270
 NCBI Accession #    NP_000605.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000614.3 [Other Products]
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 UniProt Primary Accession #    P26441 [Other Products]
 UniProt Secondary Accession #    B2RAB2 [Other Products]
 UniProt Related Accession #    P26441 [Other Products]
 Molecular Weight    22,931 Da
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 NCBI Official Full Name    ciliary neurotrophic factor
 NCBI Official Synonym Full Names    ciliary neurotrophic factor
 NCBI Official Symbol    CNTF [Similar Products]
 NCBI Official Synonym Symbols   
HCNTF
[Similar Products]
 NCBI Protein Information    ciliary neurotrophic factor
 UniProt Protein Name    Ciliary neurotrophic factor
 Protein Family    Ciliary neurotrophic factor
 UniProt Gene Name    CNTF [Similar Products]
 UniProt Synonym Gene Names    CNTF [Similar Products]
 UniProt Entry Name    CNTF_HUMAN
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 NCBI Summary for CNTF    The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
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 UniProt Comments for CNTF    CNTF: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Belongs to the CNTF family.

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: extracellular space; cytoplasm

Molecular Function: interleukin-6 receptor binding; growth factor activity; ciliary neurotrophic factor receptor binding

Biological Process: negative regulation of photoreceptor cell differentiation; positive regulation of cell proliferation; neuron development; regulation of retinal cell programmed cell death; negative regulation of neuron apoptosis; signal transduction; muscle morphogenesis; positive regulation of tyrosine phosphorylation of Stat3 protein; growth
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 Research Articles on CNTF    1. we show that the release of CNTF by glial cells is a very powerful stimulus for optic fiber regeneration and retinal ganglion cell survival after optic nerve crush
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CNTF elisa kitPathways associated with CNTF elisa kit
 Reference Product  PubMed Publications
 STAT3 elisa kit  >193 publications with CNTF and STAT3
 LIFR elisa kit  >127 publications with CNTF and LIFR
 IL6ST elisa kit  >111 publications with CNTF and IL6ST
 CNTFR elisa kit  >108 publications with CNTF and CNTFR
 GFAP elisa kit  >105 publications with CNTF and GFAP
 EGF elisa kit  >50 publications with CNTF and EGF
 SOCS3 elisa kit  >29 publications with CNTF and SOCS3
 APOE elisa kit  >4 publications with CNTF and APOE
 IL6R elisa kit  >1 publications with CNTF and IL6R
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Delta-Notch Signaling Pathway antibodies  Delta-Notch Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
Diseases associated with CNTF elisa kitOrgans/Tissues associated with CNTF elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >558 publications with CNTF and Nervous System Diseases
 Death Antibodies  >369 publications with CNTF and Death
 Brain Diseases Antibodies  >284 publications with CNTF and Brain Diseases
 Disease Models, Animal Antibodies  >221 publications with CNTF and Disease Models, Animal
 Nerve Degeneration Antibodies  >187 publications with CNTF and Nerve Degeneration
 Inflammation Antibodies  >98 publications with CNTF and Inflammation
 Drug Toxicity Antibodies  >89 publications with CNTF and Drug Toxicity
 Necrosis Antibodies  >86 publications with CNTF and Necrosis
 Weight Loss Antibodies  >72 publications with CNTF and Weight Loss
 Atrophy Antibodies  >64 publications with CNTF and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1766 publications with CNTF and Nerve
 Brain Antibodies  >1250 publications with CNTF and Brain
 Eye Antibodies  >360 publications with CNTF and Eye
 Embryonic Tissue Antibodies  >330 publications with CNTF and Embryonic Tissue
 Ganglia Antibodies  >323 publications with CNTF and Ganglia
 Muscle Antibodies  >316 publications with CNTF and Muscle
 Spinal Cord Antibodies  >274 publications with CNTF and Spinal Cord
 Blood Antibodies  >192 publications with CNTF and Blood
 Bone Antibodies  >101 publications with CNTF and Bone
 Vascular Antibodies  >71 publications with CNTF and Vascular
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