NP_066970.3
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cyclin-O
NCBI Official Synonym Full Names
cyclin O
NCBI Protein Information
cyclin-O; cyclin U; cyclin domain containing
UniProt Protein Name
Cyclin-O
UniProt Entry Name
CCNO_HUMAN
NCBI Summary for CCNO
This gene encodes a member of the cyclin protein family, and the encoded protein is involved in regulation of the cell cycle. Disruption of this gene is associated with primary ciliary dyskinesia-19. Alternative splicing results in multiple transcript variants. This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 symbol is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes. [provided by RefSeq, Jul 2014]
UniProt Comments for CCNO
CCNO: This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 term is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes.[provided by RefSeq, Nov 2010]
Protein type: Hydrolase; DNA repair, damage; Cell cycle regulation; EC 3.2.2.-
Chromosomal Location of Human Ortholog: 5q11.2
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: uracil DNA N-glycosylase activity
Biological Process: response to drug; base-excision repair; cell division; cilium biogenesis; cell cycle
Disease: Ciliary Dyskinesia, Primary, 29
Research Articles on CCNO
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Products associated with CCNO elisa kit
Pathways associated with CCNO elisa kit
Diseases associated with CCNO elisa kit
Organs/Tissues associated with CCNO elisa kit
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