NP_114414.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
64,990 Da
NCBI Official Full Name
eukaryotic translation initiation factor 2A
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2A, 65kDa
NCBI Official Synonym Symbols
CDA02; EIF-2A; MST089; MSTP004; MSTP089 [Similar Products]
NCBI Protein Information
eukaryotic translation initiation factor 2A; 65 kDa eukaryotic translation initiation factor 2A
UniProt Protein Name
Eukaryotic translation initiation factor 2A
UniProt Synonym Protein Names
65 kDa eukaryotic translation initiation factor 2A
UniProt Synonym Gene Names
UniProt Entry Name
EIF2A_HUMAN
NCBI Summary for EIF2A
EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM, Mar 2008]
UniProt Comments for EIF2A
EIF2A: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. Belongs to the WD repeat EIF2A family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation
Chromosomal Location of Human Ortholog: 3q25.1
Cellular Component: extracellular space; cytoplasm; eukaryotic translation initiation factor 2 complex
Molecular Function: protein binding; translation initiation factor activity; ribosome binding; tRNA binding
Biological Process: regulation of translation; ribosome assembly; positive regulation of signal transduction; translational initiation; SREBP-mediated signaling pathway; protein amino acid phosphorylation
Research Articles on EIF2A
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Products associated with EIF2A elisa kit
Pathways associated with EIF2A elisa kit
Diseases associated with EIF2A elisa kit
Organs/Tissues associated with EIF2A elisa kit
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